# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5207798 | 40 | Papp | = | 52.8 | 10^-6 cm/s | ALA5167373 | 10^-6 cm/s | ||||
2. | ALA5207798 | 40 | BPR | = | 0.46 | ALA5167340 | ||||||
3. | ALA5207798 | 40 | F | = | 9.4 | % | ALA5167339 | % | ||||
4. | ALA5207798 | 40 | Cmax | = | 21.4 | ng/ml | ALA5167338 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5207798 | 40 | AUC | = | 20.4 | ng.hr/ml | ALA5167337 | ng.hr.mL-1 | ||||
6. | ALA5207798 | 40 | AUC | = | 218 | ng.hr/ml | ALA5167336 | ng.hr.mL-1 | ||||
7. | ALA5207798 | 40 | Tmax | = | 0.5 | hr | ALA5167335 | hr | ||||
8. | ALA5207798 | 40 | t1/2 | = | 0.71 | hr | ALA5167334 | hr | ||||
9. | ALA5207798 | 40 | t1/2 | = | 0.2 | hr | ALA5167333 | hr | ||||
10. | ALA5207798 | 40 | Vd | = | 1.36 | L/Kg | ALA5167332 | L.kg-1 | ||||
11. | ALA5207798 | 40 | CL | = | 77.9 | ml/min.kg | ALA5167331 | mL.min-1.kg-1 | ||||
12. | ALA5207798 | 40 | Ratio | = | 0.74 | ALA5167330 | ||||||
13. | ALA5207798 | 40 | BPR | = | 0.45 | ALA5167329 | ||||||
14. | ALA5207798 | 40 | CLH | = | 26 | microL/min/mg | ALA5167328 | mL.min-1.g-1 | ||||
15. | ALA5207798 | 40 | CLH | = | 18 | microL/min/mg | ALA5167327 | mL.min-1.g-1 | ||||
16. | ALA5207798 | 40 | IC50 | > | 30 | uM | ALA5167326 | nM | Homo sapiens | |||
17. | ALA5207798 | 40 | Activity | = | 0 | % | ALA5167325 | % | Homo sapiens | |||
18. | ALA5207798 | 40 | Activity | = | -36 | % | ALA5167324 | % | Homo sapiens | |||
19. | ALA5207798 | 40 | Activity | = | -25 | % | ALA5167323 | % | Homo sapiens | |||
20. | ALA5207798 | 40 | Ki | = | 28 | nM | ALA5167322 | 7.55 | nM | Homo sapiens |