| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5207874 | AGI-44131 | Ratio | = | 6 | ALA5161769 | ||||||
| 2. | ALA5207874 | AGI-44131 | EAUC50 | = | 26100 | hr.ng/ml | ALA5161768 | hr.ng/ml | ||||
| 3. | ALA5207874 | AGI-44131 | EAUC50 | = | 4500 | hr.ng/ml | ALA5161767 | hr.ng/ml | ||||
| 4. | ALA5207874 | AGI-44131 | Activity | 0 | ALA5161755 | Toxic | ||||||
| 5. | ALA5207874 | AGI-44131 | Activity | 0 | ALA5161754 | NA | ||||||
| 6. | ALA5207874 | AGI-44131 | Activity | 0 | ALA5161753 | Toxic | ||||||
| 7. | ALA5207874 | AGI-44131 | fIC50 | = | 57 | nM | ALA5161752 | nM | ||||
| 8. | ALA5207874 | AGI-44131 | fIC50 | = | 9.8 | nM | ALA5161751 | nM | ||||
| 9. | ALA5207874 | AGI-44131 | Fu | = | 0.011 | ALA5161750 | ||||||
| 10. | ALA5207874 | AGI-44131 | AUC | = | 65.1 | ug.hr/ml | ALA5161747 | ng.hr.mL-1 | ||||
| 11. | ALA5207874 | AGI-44131 | Cmax | = | 3.43 | ug ml-1 | ALA5161746 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA5207874 | AGI-44131 | MRT | = | 11.5 | hr | ALA5161745 | hr | ||||
| 13. | ALA5207874 | AGI-44131 | Vdss | = | 1.22 | L/Kg | ALA5161744 | L.kg-1 | ||||
| 14. | ALA5207874 | AGI-44131 | ERH | = | 0.107 | ALA5161743 | ||||||
| 15. | ALA5207874 | AGI-44131 | Ratio | = | 0.7 | ALA5161742 | ||||||
| 16. | ALA5207874 | AGI-44131 | Ratio | = | 0.6 | ALA5161741 | ||||||
| 17. | ALA5207874 | AGI-44131 | permeability | = | 18 | 10^-6 cm/s | ALA5161740 | 10^-6 cm/s | ||||
| 18. | ALA5207874 | AGI-44131 | FC | = | 2.1 | ALA5161739 | Homo sapiens | |||||
| 19. | ALA5207874 | AGI-44131 | Imax | = | 89 | % | ALA5161738 | % | Homo sapiens | |||
| 20. | ALA5207874 | AGI-44131 | IC50 | = | 0.023 | uM | ALA5161737 | 7.64 | nM | Homo sapiens |
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