# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5208103 | 3h | Ct | = | 0.97 | uM | ALA5167075 | uM | ||||
2. | ALA5208103 | 3h | INH | = | 49 | % | ALA5167074 | % | Rattus norvegicus | |||
3. | ALA5208103 | 3h | Ratio | > | 2.5 | ALA5167073 | ||||||
4. | ALA5208103 | 3h | Drug uptake | = | 1.6 | % | ALA5167072 | % | ||||
5. | ALA5208103 | 3h | Drug uptake | = | 8.4 | % | ALA5167070 | % | ||||
6. | ALA5208103 | 3h | Ratio | = | 4.9 | ALA5167069 | ||||||
7. | ALA5208103 | 3h | Cmax | = | 2.7 | uM | ALA5167067 | nM | ||||
8. | ALA5208103 | 3h | Cmax | = | 0.01 | uM | ALA5167066 | nM | ||||
9. | ALA5208103 | 3h | PB | = | 99.9 | % | ALA5167063 | % | ||||
10. | ALA5208103 | 3h | PPB | = | 99.7 | % | ALA5167062 | % | ||||
11. | ALA5208103 | 3h | permeability | = | 1.4 | 10^-6 cm/s | ALA5167060 | 10^-6 cm/s | ||||
12. | ALA5208103 | 3h | solubility | = | 0.1 | mg/ml | ALA5167059 | ug.mL-1 | ||||
13. | ALA5208103 | 3h | IC50 | > | 10000 | nM | ALA5167058 | nM | Homo sapiens | |||
14. | ALA5208103 | 3h | IC50 | = | 2856 | nM | ALA5167057 | 5.54 | nM | Homo sapiens | ||
15. | ALA5208103 | 3h | IC50 | = | 1.3 | nM | ALA5167056 | 8.89 | nM | Homo sapiens | ||
16. | ALA5208103 | 3h | t1/2 | > | 16 | hr | ALA5167055 | hr | Homo sapiens | |||
17. | ALA5208103 | 3h | IC50 | = | 1 | nM | ALA5167054 | 9.00 | nM | |||
18. | ALA5208103 | 3h | IC50 | = | 0.2 | nM | ALA5167053 | 9.70 | nM | Homo sapiens | ||
19. | ALA5208103 | 3h | t1/2 | = | 20 | min | ALA5167052 | hr |