Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5209256	14	t1/2	=	8.94	hr	ALA5122386			hr
2.	ALA5209256	14	Tmax	=	2	hr	ALA5122385			hr
3.	ALA5209256	14	Cmax	=	100	ng/ml	ALA5122384		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
4.	ALA5209256	14	AUC	=	852	ng/mL.hr	ALA5122383			ng.hr.mL-1
5.	ALA5209256	14	Tmax	=	1	hr	ALA5122382			hr
6.	ALA5209256	14	Cmax	=	586	ng/ml	ALA5122381		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
7.	ALA5209256	14	AUC	=	4658	ng/mL.hr	ALA5122380			ng.hr.mL-1
8.	ALA5209256	14	ED50	=	2.9	mg kg-1	ALA5122379			mg.kg-1	Mus musculus
9.	ALA5209256	14	ED50	=	8.1	mg kg-1	ALA5122378			mg.kg-1	Mus musculus
10.	ALA5209256	14	Activity		0		ALA5122377		Active		Mus musculus
11.	ALA5209256	14	Stability	=	73	%	ALA5122376			%
12.	ALA5209256	14	Stability	=	84	%	ALA5122375			%
13.	ALA5209256	14	Stability	=	95	%	ALA5122374			%
14.	ALA5209256	14	EC50	=	637	nM	ALA5122373	6.20		nM	Homo sapiens
15.	ALA5209256	14	FC	=	4.1		ALA5122372				Homo sapiens

1.

ALA5209256

14

t1/2

=

8.94

hr

ALA5122386

hr

2.

ALA5209256

14

Tmax

=

2

hr

ALA5122385

hr

3.

ALA5209256

14

Cmax

=

100

ng/ml

ALA5122384

standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW

nM

4.

ALA5209256

14

AUC

=

852

ng/mL.hr

ALA5122383

ng.hr.mL-1

5.

ALA5209256

14

Tmax

=

1

hr

ALA5122382

hr

6.

ALA5209256

14

Cmax

=

586

ng/ml

ALA5122381

standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW

nM

7.

ALA5209256

14

AUC

=

4658

ng/mL.hr

ALA5122380

ng.hr.mL-1

8.

ALA5209256

14

ED50

=

2.9

mg kg-1

ALA5122379

mg.kg-1

Mus musculus

9.

ALA5209256

14

ED50

=

8.1

mg kg-1

ALA5122378

mg.kg-1

Mus musculus

10.

ALA5209256

14

Activity

0

ALA5122377

Active

Mus musculus

11.

ALA5209256

14

Stability

=

73

%

ALA5122376

%

12.

ALA5209256

14

Stability

=

84

%

ALA5122375

%

13.

ALA5209256

14

Stability

=

95

%

ALA5122374

%

14.

ALA5209256

14

EC50

=

637

nM

ALA5122373

6.20

nM

Homo sapiens

15.

ALA5209256

14

FC

=

4.1

ALA5122372

Homo sapiens