# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5218472 | 59 | Vz | = | 2.09 | L/Kg | ALA5217074 | L.kg-1 | ||||
2. | ALA5218472 | 59 | CL | = | 3.18 | L/hr/kg | ALA5217073 | mL.min-1.kg-1 | ||||
3. | ALA5218472 | 59 | AUC | = | 631.6 | hr.ng/ml | ALA5217072 | ng.hr.mL-1 | ||||
4. | ALA5218472 | 59 | Cmax | = | 2123.33 | ng/ml | ALA5217071 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5218472 | 59 | t1/2 | = | 0.46 | hr | ALA5217070 | hr | ||||
6. | ALA5218472 | 59 | Activity | 0 | ALA5217069 | Dde | ||||||
7. | ALA5218472 | 59 | Activity | 0 | ALA5217068 | Dde | ||||||
8. | ALA5218472 | 59 | Activity | 0 | ALA5217067 | Dde | ||||||
9. | ALA5218472 | 59 | Ratio IC50 | = | 119 | ALA5217066 | ||||||
10. | ALA5218472 | 59 | Ratio IC50 | > | 385 | ALA5217065 | ||||||
11. | ALA5218472 | 59 | IC50 | = | 1547 | nM | ALA5217064 | 5.81 | nM | Homo sapiens | ||
12. | ALA5218472 | 59 | IC50 | > | 5000 | nM | ALA5217063 | nM | Homo sapiens | |||
13. | ALA5218472 | 59 | Ratio IC50 | = | 13 | ALA5217062 | ||||||
14. | ALA5218472 | 59 | Ratio IC50 | = | 73 | ALA5217061 | ||||||
15. | ALA5218472 | 59 | IC50 | = | 30.5 | nM | ALA5217060 | 7.52 | nM | Homo sapiens | ||
16. | ALA5218472 | 59 | IC50 | = | 168.9 | nM | ALA5217059 | 6.77 | nM | Homo sapiens | ||
17. | ALA5218472 | 59 | IC50 | = | 37.04 | uM | ALA5217058 | 4.43 | nM | Homo sapiens | ||
18. | ALA5218472 | 59 | IC50 | = | 0.15 | uM | ALA5217057 | 6.82 | nM | Homo sapiens | ||
19. | ALA5218472 | 59 | IC50 | = | 0.042 | uM | ALA5217056 | 7.38 | nM | Homo sapiens | ||
20. | ALA5218472 | 59 | IC50 | = | 0.8 | uM | ALA5217055 | 6.10 | nM | Homo sapiens |