# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5218726 | 38 | F | = | 19 | % | ALA5218166 | % | ||||
2. | ALA5218726 | 38 | t1/2 | = | 0.41 | hr | ALA5218165 | hr | ||||
3. | ALA5218726 | 38 | Vduss | = | 1.8 | L/Kg | ALA5218164 | L.kg-1 | ||||
4. | ALA5218726 | 38 | Vdss | = | 1 | L/Kg | ALA5218163 | L.kg-1 | ||||
5. | ALA5218726 | 38 | CL free | = | 75 | ml/min.kg | ALA5218162 | mL.min-1.kg-1 | ||||
6. | ALA5218726 | 38 | CL | = | 43 | ml/min.kg | ALA5218161 | mL.min-1.kg-1 | ||||
7. | ALA5218726 | 38 | CLH | = | 0.52 | ml/min/g | ALA5218160 | mL.min-1.g-1 | ||||
8. | ALA5218726 | 38 | CLH | < | 0.65 | ml/min/g | ALA5218159 | mL.min-1.g-1 | ||||
9. | ALA5218726 | 38 | CLH | < | 0.8 | ml/min/g | ALA5218158 | mL.min-1.g-1 | ||||
10. | ALA5218726 | 38 | solubility | > | 1000 | ug ml-1 | ALA5218157 | ug.mL-1 | ||||
11. | ALA5218726 | 38 | permeability | = | 8 | nm/s | ALA5218155 | nm/s | ||||
12. | ALA5218726 | 38 | logD | = | 0.8 | ALA5218151 | ||||||
13. | ALA5218726 | 38 | pIC50 | = | 7.4 | ALA5218150 | 7.40 | nM | Homo sapiens | |||
14. | ALA5218726 | 38 | pIC50 | = | 7.8 | ALA5218149 | 7.80 | nM | Homo sapiens | |||
15. | ALA5218726 | 38 | pIC50 | = | 7.6 | ALA5218148 | 7.60 | nM | Homo sapiens |