# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5219823 | 36 | F | = | 90 | % | ALA5217953 | % | ||||
2. | ALA5219823 | 36 | CL | = | 179 | ml/min.kg | ALA5217952 | mL.min-1.kg-1 | ||||
3. | ALA5219823 | 36 | AUClast | = | 4332 | hr.ng/ml | ALA5217951 | ng.hr.mL-1 | ||||
4. | ALA5219823 | 36 | Cmax | = | 5580 | ng/ml | ALA5217950 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5219823 | 36 | Tmax | = | 0.25 | hr | ALA5217949 | hr | ||||
6. | ALA5219823 | 36 | t1/2 | = | 0.45 | hr | ALA5217948 | hr | ||||
7. | ALA5219823 | 36 | t1/2 | = | 2.87 | hr | ALA5217947 | hr | ||||
8. | ALA5219823 | 36 | Stability | = | 40 | % | ALA5217946 | % | ||||
9. | ALA5219823 | 36 | Stability | = | 57 | % | ALA5217945 | % | ||||
10. | ALA5219823 | 36 | IC50 | = | 79 | nM | ALA5217944 | 7.10 | nM | Homo sapiens | ||
11. | ALA5219823 | 36 | IC50 | = | 92 | nM | ALA5217943 | 7.04 | nM | Homo sapiens |