# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5220883 | 21.HCl | Activity | 0 | ALA5217516 | Active | enterovirus D68 | |||||
2. | ALA5220883 | 21.HCl | Activity | 0 | ALA5217515 | Dde | enterovirus D68 | |||||
3. | ALA5220883 | 21.HCl | Activity | 0 | ALA5217514 | Dde | enterovirus D68 | |||||
4. | ALA5220883 | 21.HCl | F | = | 6.8 | % | ALA5217513 | % | ||||
5. | ALA5220883 | 21.HCl | AUC | = | 53.8 | hr.ng/ml | ALA5217512 | ng.hr.mL-1 | ||||
6. | ALA5220883 | 21.HCl | AUC | = | 49.5 | hr.ng/ml | ALA5217511 | ng.hr.mL-1 | ||||
7. | ALA5220883 | 21.HCl | Tmax | = | 0.417 | hr | ALA5217510 | hr | ||||
8. | ALA5220883 | 21.HCl | Cmax | = | 36.1 | ng/ml | ALA5217509 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA5220883 | 21.HCl | t1/2 | = | 1.06 | hr | ALA5217508 | hr | ||||
10. | ALA5220883 | 21.HCl | AUC | = | 158 | hr.ng/ml | ALA5217507 | ng.hr.mL-1 | ||||
11. | ALA5220883 | 21.HCl | AUCt | = | 157 | hr.ng/ml | ALA5217506 | ng.hr.mL-1 | ||||
12. | ALA5220883 | 21.HCl | CL | = | 106 | ml/min.kg | ALA5217505 | mL.min-1.kg-1 | ||||
13. | ALA5220883 | 21.HCl | t1/2 | = | 0.309 | hr | ALA5217504 | hr | ||||
14. | ALA5220883 | 21.HCl | C0 | = | 1370 | ng/ml | ALA5217503 | ng/ml | ||||
15. | ALA5220883 | 21.HCl | Ratio CC50/EC50 | > | 159 | ALA5217502 | ||||||
16. | ALA5220883 | 21.HCl | EC50 | = | 0.07 | uM | ALA5217501 | 7.16 | nM | enterovirus D68 | ||
17. | ALA5220883 | 21.HCl | Ratio CC50/EC50 | > | 185 | ALA5217500 | ||||||
18. | ALA5220883 | 21.HCl | Ratio CC50/EC50 | > | 159 | ALA5217499 | ||||||
19. | ALA5220883 | 21.HCl | EC50 | = | 0.06 | uM | ALA5217498 | 7.22 | nM | enterovirus D68 | ||
20. | ALA5220883 | 21.HCl | EC50 | = | 0.07 | uM | ALA5217497 | 7.16 | nM | enterovirus D68 |