# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5220885 | 51 | F | = | 1.7 | % | ALA5217748 | % | ||||
2. | ALA5220885 | 51 | MRTlast | = | 1.98 | hr | ALA5217747 | hr | ||||
3. | ALA5220885 | 51 | AUClast | = | 209 | hr.ng/ml | ALA5217746 | ng.hr.mL-1 | ||||
4. | ALA5220885 | 51 | MRTlast | = | 0.35 | hr | ALA5217745 | hr | ||||
5. | ALA5220885 | 51 | Vdss | = | 0.3 | L/Kg | ALA5217744 | L.kg-1 | ||||
6. | ALA5220885 | 51 | CL | = | 13.5 | ml/min.kg | ALA5217743 | mL.min-1.kg-1 | ||||
7. | ALA5220885 | 51 | AUClast | = | 3126 | hr.ng/ml | ALA5217742 | ng.hr.mL-1 | ||||
8. | ALA5220885 | 51 | C0 | = | 9647 | ng/ml | ALA5217741 | ng/ml | ||||
9. | ALA5220885 | 51 | Tmax | = | 0.5 | hr | ALA5217739 | hr | ||||
10. | ALA5220885 | 51 | Cmax | = | 113 | ng/ml | ALA5217738 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
11. | ALA5220885 | 51 | t1/2 | = | 1.15 | hr | ALA5217737 | hr | ||||
12. | ALA5220885 | 51 | t1/2 | = | 0.41 | hr | ALA5217733 | hr | ||||
13. | ALA5220885 | 51 | IC50 | = | 0.03 | uM | ALA5217732 | 7.52 | nM | |||
14. | ALA5220885 | 51 | Ki | = | 18.5 | nM | ALA5217731 | 7.73 | nM | Homo sapiens | ||
15. | ALA5220885 | 51 | IC50 | = | 0.037 | uM | ALA5217731 | 7.43 | nM | Homo sapiens |