# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5221106 | 35 | F | = | 191 | % | ALA5217953 | % | ||||
2. | ALA5221106 | 35 | CL | = | 182 | ml/min.kg | ALA5217952 | mL.min-1.kg-1 | ||||
3. | ALA5221106 | 35 | AUClast | = | 9219 | hr.ng/ml | ALA5217951 | ng.hr.mL-1 | ||||
4. | ALA5221106 | 35 | Cmax | = | 13533 | ng/ml | ALA5217950 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5221106 | 35 | Tmax | = | 0.25 | hr | ALA5217949 | hr | ||||
6. | ALA5221106 | 35 | t1/2 | = | 0.37 | hr | ALA5217948 | hr | ||||
7. | ALA5221106 | 35 | t1/2 | = | 0.543 | hr | ALA5217947 | hr | ||||
8. | ALA5221106 | 35 | Stability | = | 47 | % | ALA5217946 | % | ||||
9. | ALA5221106 | 35 | Stability | = | 85 | % | ALA5217945 | % | ||||
10. | ALA5221106 | 35 | IC50 | = | 23 | nM | ALA5217944 | 7.64 | nM | Homo sapiens | ||
11. | ALA5221106 | 35 | IC50 | = | 102 | nM | ALA5217943 | 6.99 | nM | Homo sapiens |