Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5266492	27	Activity		0		ALA5228474		Active		Leishmania mexicana
2.	ALA5266492	27	Vd	=	25.9	L/Kg	ALA5228461			L.kg-1
3.	ALA5266492	27	CL	=	7.7	L/hr/kg	ALA5228460			mL.min-1.kg-1
4.	ALA5266492	27	AUC	=	3.91	uM.hr	ALA5228459		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW	ng.hr.mL-1
5.	ALA5266492	27	Tmax		0		ALA5228458		Not Determined
6.	ALA5266492	27	Cmax	=	0.741	uM	ALA5228457			nM
7.	ALA5266492	27	t1/2	=	2.32	hr	ALA5228456			hr
8.	ALA5266492	27	CLH	=	210	ml/min.kg	ALA5228455			mL.min-1.kg-1
9.	ALA5266492	27	t1/2	=	0.17	hr	ALA5228454			hr
10.	ALA5266492	27	Selectivity Index	=	17		ALA5228448
11.	ALA5266492	27	EC50	=	3.7	uM	ALA5228447	5.43		nM	Mus musculus
12.	ALA5266492	27	EC50	=	0.22	uM	ALA5228446	6.66		nM	Leishmania mexicana