Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5267842	PALTUSOTINE	INH		0		ALA5225710		Active	%	Canis lupus familiaris
2.	ALA5267842	PALTUSOTINE	INH		0		ALA5225709		Active	%	Canis lupus familiaris
3.	ALA5267842	PALTUSOTINE	INH		0		ALA5225708		Active	%	Rattus norvegicus
4.	ALA5267842	PALTUSOTINE	INH		0		ALA5225707		Active	%	Rattus norvegicus
5.	ALA5267842	PALTUSOTINE	INH		0		ALA5225706		Active	%	Rattus norvegicus
6.	ALA5267842	PALTUSOTINE	INH		0		ALA5225705		Active	%	Rattus norvegicus
7.	ALA5267842	PALTUSOTINE	INH		0		ALA5225704		Dose-Dependent Effect	%	Rattus norvegicus
8.	ALA5267842	PALTUSOTINE	INH		0		ALA5225703		Dose-Dependent Effect	%	Rattus norvegicus
9.	ALA5267842	PALTUSOTINE	EC50	=	6.6	nM	ALA5225702	8.18		nM	Canis lupus familiaris
10.	ALA5267842	PALTUSOTINE	EC50	=	1.2	nM	ALA5225701	8.92		nM	Rattus norvegicus
11.	ALA5267842	PALTUSOTINE	Ratio	=	34		ALA5225700
12.	ALA5267842	PALTUSOTINE	Papp	=	0.62	10^-6 cm/s	ALA5225699			10^-6 cm/s
13.	ALA5267842	PALTUSOTINE	F	=	48	%	ALA5225698			%
14.	ALA5267842	PALTUSOTINE	AUC	=	10430	ng.hr/ml	ALA5225697			ng.hr.mL-1
15.	ALA5267842	PALTUSOTINE	Cmax	=	1367	ng/ml	ALA5225696		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
16.	ALA5267842	PALTUSOTINE	Vdss	=	3.5	L/Kg	ALA5225695			L.kg-1
17.	ALA5267842	PALTUSOTINE	CL	=	9.4	ml/min.kg	ALA5225694			mL.min-1.kg-1
18.	ALA5267842	PALTUSOTINE	t1/2	=	7.5	hr	ALA5225693			hr
19.	ALA5267842	PALTUSOTINE	F	=	8.8	%	ALA5225692			%
20.	ALA5267842	PALTUSOTINE	Cmax	=	129	ng/ml	ALA5225691		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM