# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5267968 | 26 | Ratio IC50 | = | 1.5 | ALA5239179 | ||||||
2. | ALA5267968 | 26 | IC50 | = | 18 | nM | ALA5239178 | 7.75 | nM | Mus musculus | ||
3. | ALA5267968 | 26 | IC50 | = | 27 | nM | ALA5239177 | 7.57 | nM | Mus musculus | ||
4. | ALA5267968 | 26 | Ratio IC50 | = | 0.7 | ALA5239176 | ||||||
5. | ALA5267968 | 26 | IC50 | = | 20 | nM | ALA5239175 | 7.70 | nM | |||
6. | ALA5267968 | 26 | IC50 | = | 1 | nM | ALA5239174 | 9.00 | nM | Rattus norvegicus | ||
7. | ALA5267968 | 26 | Ratio IC50 | = | 1.5 | ALA5239173 | ||||||
8. | ALA5267968 | 26 | IC50 | = | 13 | nM | ALA5239172 | 7.89 | nM | Homo sapiens | ||
9. | ALA5267968 | 26 | IC50 | = | 19 | nM | ALA5239171 | 7.72 | nM | Homo sapiens | ||
10. | ALA5267968 | 26 | F | = | 95 | % | ALA5239163 | % | ||||
11. | ALA5267968 | 26 | AUCt | = | 56.1 | uM.hr | ALA5239162 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
12. | ALA5267968 | 26 | Cmax | = | 11.1 | uM | ALA5239161 | nM | ||||
13. | ALA5267968 | 26 | CLH | < | 1 | uL/min | ALA5239160 | uL/min | ||||
14. | ALA5267968 | 26 | Ratio | = | 1.1 | ALA5239159 | ||||||
15. | ALA5267968 | 26 | Papp | = | 9.9 | 10^-6 cm/s | ALA5239158 | 10^-6 cm/s | ||||
16. | ALA5267968 | 26 | IC50 | = | 6 | uM | ALA5239155 | 5.22 | nM | Homo sapiens | ||
17. | ALA5267968 | 26 | IC50 | < | 50 | uM | ALA5239154 | nM | Homo sapiens |