# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5268064 | 12k | Activity | 0 | ALA5223868 | Not Active | Rattus norvegicus | |||||
2. | ALA5268064 | 12k | BPR | = | 0.8 | ALA5223858 | ||||||
3. | ALA5268064 | 12k | CL | = | 126 | ml/min.kg | ALA5223857 | mL.min-1.kg-1 | ||||
4. | ALA5268064 | 12k | Vdss | = | 12.7 | L/Kg | ALA5223856 | L.kg-1 | ||||
5. | ALA5268064 | 12k | beta t1/2 | = | 1.2 | hr | ALA5223855 | hr | ||||
6. | ALA5268064 | 12k | AUC | = | 74 | ng.hr/ml | ALA5223854 | ng.hr.mL-1 | ||||
7. | ALA5268064 | 12k | Cmax | = | 43 | ng/ml | ALA5223853 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA5268064 | 12k | F | = | 19 | % | ALA5223852 | % | ||||
9. | ALA5268064 | 12k | INH | = | 0 | % | ALA5223851 | % | Homo sapiens | |||
10. | ALA5268064 | 12k | IC50 | > | 45 | uM | ALA5223850 | nM | Homo sapiens | |||
11. | ALA5268064 | 12k | IC50 | > | 45 | uM | ALA5223849 | nM | Homo sapiens | |||
12. | ALA5268064 | 12k | INH | = | 36 | % | ALA5223848 | % | Homo sapiens | |||
13. | ALA5268064 | 12k | IC50 | > | 10 | uM | ALA5223847 | nM | Homo sapiens | |||
14. | ALA5268064 | 12k | Drug metabolism | = | 53.8 | % | ALA5223846 | % | ||||
15. | ALA5268064 | 12k | Drug metabolism | = | 79.2 | % | ALA5223845 | % | ||||
16. | ALA5268064 | 12k | Emax | = | 26 | % | ALA5223844 | % | Homo sapiens | |||
17. | ALA5268064 | 12k | EC50 | = | 158 | nM | ALA5223843 | 6.80 | nM | Homo sapiens |