Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5268258	23	F	=	20	%	ALA5238929			%
2.	ALA5268258	23	Cmax	=	0.72	uM	ALA5238928			nM
3.	ALA5268258	23	AUCt	=	6.19	uM.hr	ALA5238927		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW	ng.hr.mL-1
4.	ALA5268258	23	MRT	=	3.6	hr	ALA5238926			hr
5.	ALA5268258	23	t1/2	=	3.9	hr	ALA5238925			hr
6.	ALA5268258	23	Vdss	=	0.8	L/Kg	ALA5238924			L.kg-1
7.	ALA5268258	23	CL	=	3.7	ml/min.kg	ALA5238923			mL.min-1.kg-1
8.	ALA5268258	23	solubility	>	480	uM	ALA5238922			nM
9.	ALA5268258	23	solubility	<	1	uM	ALA5238921			nM
10.	ALA5268258	23	PPB	=	89	%	ALA5238920			%	Homo sapiens
11.	ALA5268258	23	t1/2	>	120	min	ALA5238919			hr
12.	ALA5268258	23	t1/2	>	120	min	ALA5238918			hr
13.	ALA5268258	23	t1/2	>	120	min	ALA5238917			hr
14.	ALA5268258	23	EC50	=	5.1	nM	ALA5238916	8.29		nM	Human immunodeficiency virus 1
15.	ALA5268258	23	EC50	=	8	nM	ALA5238915	8.10		nM	Human immunodeficiency virus 1
16.	ALA5268258	23	CC50	=	16	uM	ALA5238914			nM	Homo sapiens
17.	ALA5268258	23	FC	=	6.3		ALA5238913
18.	ALA5268258	23	EC50	=	3.8	nM	ALA5238911	8.42		nM	Human immunodeficiency virus 1
19.	ALA5268258	23	EC50	=	8.1	nM	ALA5238910	8.09		nM	Human immunodeficiency virus 1
20.	ALA5268258	23	EC50	=	6	nM	ALA5238909	8.22		nM	Human immunodeficiency virus 1