Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5269677	49b	Ratio IC50	=	3.5		ALA5259894
2.	ALA5269677	49b	Ratio IC50	>	41		ALA5259893
3.	ALA5269677	49b	Ratio IC50	=	17		ALA5259892
4.	ALA5269677	49b	INH		0		ALA5259891		Dose-Dependent Effect	%
5.	ALA5269677	49b	F	=	91.8	%	ALA5259890			%
6.	ALA5269677	49b	CL	=	1.23	L/hr/kg	ALA5259889			mL.min-1.kg-1
7.	ALA5269677	49b	CL	=	0.94	L/hr/kg	ALA5259888			mL.min-1.kg-1
8.	ALA5269677	49b	Vd	=	3.13	L/Kg	ALA5259887			L.kg-1
9.	ALA5269677	49b	Vd	=	6.36	L/Kg	ALA5259886			L.kg-1
10.	ALA5269677	49b	AUCt	=	717.19	hr.ng/ml	ALA5259885			ng.hr.mL-1
11.	ALA5269677	49b	AUCt	=	3294.5	hr.ng/ml	ALA5259884			ng.hr.mL-1
12.	ALA5269677	49b	Cmax	=	567.1	ng/ml	ALA5259883		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
13.	ALA5269677	49b	Cmax	=	863.2	ng/ml	ALA5259882		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
14.	ALA5269677	49b	t1/2	=	2.52	hr	ALA5259881			hr
15.	ALA5269677	49b	t1/2	=	4.97	hr	ALA5259880			hr
16.	ALA5269677	49b	IC50	=	1.82	uM	ALA5259879	5.74		nM	Homo sapiens
17.	ALA5269677	49b	IC50	=	1.64	uM	ALA5259878	5.79		nM	Homo sapiens
18.	ALA5269677	49b	IC50	=	0.83	uM	ALA5259877	6.08		nM	Homo sapiens
19.	ALA5269677	49b	IC50	>	10	uM	ALA5259876			nM	Homo sapiens
20.	ALA5269677	49b	IC50	=	4.1	uM	ALA5259875	5.39		nM	Homo sapiens