Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5270058	4; AZD1283	solubility	=	2.99	uM	ALA5233418			nM
2.	ALA5270058	4; AZD1283	solubility	=	0.51	uM	ALA5233417			nM
3.	ALA5270058	4; AZD1283	solubility	=	15.61	uM	ALA5233416			nM
4.	ALA5270058	4; AZD1283	IC50	=	3.64	uM	ALA5233415	5.44		nM	Homo sapiens
5.	ALA5270058	4; AZD1283	IC50	=	4.28	uM	ALA5233414	5.37		nM	Homo sapiens
6.	ALA5270058	4; AZD1283	IC50	>	25	uM	ALA5233413			nM	Homo sapiens
7.	ALA5270058	4; AZD1283	IC50	=	0.399	uM	ALA5233412	6.40		nM	Homo sapiens
8.	ALA5270058	4; AZD1283	IC50	=	6.62	uM	ALA5233411	5.18		nM	Homo sapiens
9.	ALA5270058	4; AZD1283	IC50	>	25	uM	ALA5233410			nM	Homo sapiens
10.	ALA5270058	4; AZD1283	MRT	=	2.67	hr	ALA5233409			hr
11.	ALA5270058	4; AZD1283	AUC	=	34	ng.hr/ml	ALA5233408			ng.hr.mL-1
12.	ALA5270058	4; AZD1283	Tmax	=	0.25	hr	ALA5233407			hr
13.	ALA5270058	4; AZD1283	t1/2	=	1.68	hr	ALA5233406			hr
14.	ALA5270058	4; AZD1283	Cmax	=	25.9	ng/ml	ALA5233405		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
15.	ALA5270058	4; AZD1283	CLH	=	32.3	ml/min.g	ALA5233404			ml/min.g
16.	ALA5270058	4; AZD1283	CLH	=	11.2	ml/min.g	ALA5233403			ml/min.g
17.	ALA5270058	4; AZD1283	CLH	=	345	ml/min.g	ALA5233402			ml/min.g
18.	ALA5270058	4; AZD1283	t1/2	=	65	min	ALA5233401			hr
19.	ALA5270058	4; AZD1283	t1/2	=	201	min	ALA5233400			hr
20.	ALA5270058	4; AZD1283	t1/2	=	6.08	min	ALA5233399			hr