# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5270507 | 45; DFL23448 | IC50 | = | 0.076 | uM | ALA5265525 | 7.12 | nM | Homo sapiens | ||
2. | ALA5270507 | 45; DFL23448 | IC50 | = | 0.06 | uM | ALA5265524 | 7.22 | nM | Homo sapiens | ||
3. | ALA5270507 | 45; DFL23448 | IC50 | = | 0.05 | uM | ALA5265523 | 7.30 | nM | Homo sapiens | ||
4. | ALA5270507 | 45; DFL23448 | IC50 | = | 0.075 | uM | ALA5265522 | 7.12 | nM | Homo sapiens | ||
5. | ALA5270507 | 45; DFL23448 | IC50 | > | 30 | uM | ALA5265521 | nM | Homo sapiens | |||
6. | ALA5270507 | 45; DFL23448 | IC50 | = | 0.25 | uM | ALA5265520 | 6.60 | nM | Homo sapiens | ||
7. | ALA5270507 | 45; DFL23448 | IC50 | = | 36 | nM | ALA5265519 | 7.44 | nM | Homo sapiens | ||
8. | ALA5270507 | 45; DFL23448 | Stability | = | 92 | % | ALA5265516 | % | ||||
9. | ALA5270507 | 45; DFL23448 | Stability | = | 95 | % | ALA5265515 | % | ||||
10. | ALA5270507 | 45; DFL23448 | t1/2 | = | 56.7 | min | ALA5265514 | hr | ||||
11. | ALA5270507 | 45; DFL23448 | IC50 | = | 21.4 | nM | ALA5265513 | 7.67 | nM | Homo sapiens | ||
12. | ALA5270507 | 45; DFL23448 | IC50 | = | 24 | nM | ALA5265512 | 7.62 | nM | Homo sapiens | ||
13. | ALA5270507 | 45; DFL23448 | solubility | = | 0.631 | mM | ALA5265510 | nM | ||||
14. | ALA5270507 | 45; DFL23448 | F | = | 1 | % | ALA5265509 | % | ||||
15. | ALA5270507 | 45; DFL23448 | t1/2 | = | 5.11 | hr | ALA5265508 | hr | ||||
16. | ALA5270507 | 45; DFL23448 | Cmax | = | 47 | ng/ml | ALA5265507 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
17. | ALA5270507 | 45; DFL23448 | t1/2 | = | 0.74 | hr | ALA5265503 | hr | ||||
18. | ALA5270507 | 45; DFL23448 | Vdss | = | 0.082 | L/Kg | ALA5265502 | L.kg-1 | ||||
19. | ALA5270507 | 45; DFL23448 | CL | = | 3.11 | ml/min.kg | ALA5265501 | mL.min-1.kg-1 | ||||
20. | ALA5270507 | 45; DFL23448 | t1/2 | > | 5 | min | ALA5265497 | hr |