# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5270581 | 18 | Activity | 0 | ALA5252943 | Not Active | Mus musculus | |||||
2. | ALA5270581 | 18 | Activity | 0 | ALA5252942 | Active | Mus musculus | |||||
3. | ALA5270581 | 18 | Ct | = | 440 | nM | ALA5252941 | nM | ||||
4. | ALA5270581 | 18 | Ratio | = | 0.2 | ALA5252940 | ||||||
5. | ALA5270581 | 18 | IC50 | = | 9.8 | nM | ALA5252935 | 8.01 | nM | Homo sapiens | ||
6. | ALA5270581 | 18 | IC50 | = | 5.5 | nM | ALA5252934 | 8.26 | nM | Homo sapiens | ||
7. | ALA5270581 | 18 | IC50 | = | 320 | nM | ALA5252933 | 6.50 | nM | Homo sapiens | ||
8. | ALA5270581 | 18 | Stability | = | 50 | % | ALA5252921 | % | ||||
9. | ALA5270581 | 18 | Stability | = | 88 | % | ALA5252920 | % | ||||
10. | ALA5270581 | 18 | Stability | = | 93 | % | ALA5252919 | % | ||||
11. | ALA5270581 | 18 | permeability | = | 319 | nm/s | ALA5252918 | nm/s | ||||
12. | ALA5270581 | 18 | permeability | = | 301 | nm/s | ALA5252917 | nm/s | ||||
13. | ALA5270581 | 18 | Ratio | = | 0.95 | ALA5252916 | ||||||
14. | ALA5270581 | 18 | permeability | = | 526 | nm/s | ALA5252915 | nm/s | ||||
15. | ALA5270581 | 18 | permeability | = | 483 | nm/s | ALA5252914 | nm/s | ||||
16. | ALA5270581 | 18 | Drug degradation | = | 24 | % | ALA5252911 | % | ||||
17. | ALA5270581 | 18 | Stability | 0 | ALA5252910 | Stable | % | |||||
18. | ALA5270581 | 18 | CL | = | 24 | ml/min.kg | ALA5252909 | mL.min-1.kg-1 | ||||
19. | ALA5270581 | 18 | CL | = | 9.6 | ml/min.kg | ALA5252908 | mL.min-1.kg-1 | ||||
20. | ALA5270581 | 18 | IC50 | > | 20 | uM | ALA5252907 | nM | Homo sapiens |