Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5270858	12h	Activity		0		ALA5223869		Not Active		Rattus norvegicus
2.	ALA5270858	12h	Activity		0		ALA5223866		Active		Rattus norvegicus
3.	ALA5270858	12h	BPR	=	4		ALA5223858
4.	ALA5270858	12h	CL	=	96	ml/min.kg	ALA5223857			mL.min-1.kg-1
5.	ALA5270858	12h	Vdss	=	10	L/Kg	ALA5223856			L.kg-1
6.	ALA5270858	12h	beta t1/2	=	1.7	hr	ALA5223855			hr
7.	ALA5270858	12h	AUC	=	392	ng.hr/ml	ALA5223854			ng.hr.mL-1
8.	ALA5270858	12h	Cmax	=	248	ng/ml	ALA5223853		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
9.	ALA5270858	12h	F	=	22	%	ALA5223852			%
10.	ALA5270858	12h	INH	=	0	%	ALA5223851			%	Homo sapiens
11.	ALA5270858	12h	IC50	=	37	uM	ALA5223850	4.43		nM	Homo sapiens
12.	ALA5270858	12h	IC50	>	45	uM	ALA5223849			nM	Homo sapiens
13.	ALA5270858	12h	INH	=	79	%	ALA5223848			%	Homo sapiens
14.	ALA5270858	12h	IC50	=	2.4	uM	ALA5223847	5.62		nM	Homo sapiens
15.	ALA5270858	12h	Drug metabolism	=	64.8	%	ALA5223846			%
16.	ALA5270858	12h	Drug metabolism	=	64.9	%	ALA5223845			%
17.	ALA5270858	12h	Emax	=	41	%	ALA5223844			%	Homo sapiens
18.	ALA5270858	12h	EC50	=	127	nM	ALA5223843	6.90		nM	Homo sapiens