# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5271137 | 17 | IC50 | = | 0.11 | uM | ALA5236886 | 6.96 | nM | Homo sapiens | ||
2. | ALA5271137 | 17 | IC50 | = | 0.06 | uM | ALA5236885 | 7.22 | nM | Homo sapiens | ||
3. | ALA5271137 | 17 | Stability | = | 0.7 | % | ALA5236884 | % | ||||
4. | ALA5271137 | 17 | Stability | = | 99.3 | % | ALA5236883 | % | ||||
5. | ALA5271137 | 17 | CLH | < | 11 | ml/min.kg | ALA5236881 | mL.min-1.kg-1 | ||||
6. | ALA5271137 | 17 | CLH | < | 5 | ml/min.kg | ALA5236880 | mL.min-1.kg-1 | ||||
7. | ALA5271137 | 17 | Ratio | = | 1.2 | ALA5236879 | ||||||
8. | ALA5271137 | 17 | Papp | = | 4.5 | 10^-6 cm/s | ALA5236878 | 10^-6 cm/s | ||||
9. | ALA5271137 | 17 | IC50 | = | 737 | nM | ALA5236877 | 6.13 | nM | Homo sapiens | ||
10. | ALA5271137 | 17 | IC50 | = | 18 | nM | ALA5236876 | 7.75 | nM | Homo sapiens |