# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5271471 | 6 | AUC | = | 2.6 | uM.hr | ALA5248085 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
2. | ALA5271471 | 6 | AUC | = | 21.5 | uM.hr | ALA5248084 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
3. | ALA5271471 | 6 | AUC | = | 9.3 | uM.hr | ALA5248083 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ALA5271471 | 6 | t1/2 | = | 3.7 | hr | ALA5248082 | hr | ||||
5. | ALA5271471 | 6 | t1/2 | = | 3.3 | hr | ALA5248081 | hr | ||||
6. | ALA5271471 | 6 | t1/2 | = | 3.3 | hr | ALA5248080 | hr | ||||
7. | ALA5271471 | 6 | Vdss | = | 0.64 | L/Kg | ALA5248079 | L.kg-1 | ||||
8. | ALA5271471 | 6 | Vdss | = | 5.3 | L/Kg | ALA5248078 | L.kg-1 | ||||
9. | ALA5271471 | 6 | Vdss | = | 3.2 | L/Kg | ALA5248077 | L.kg-1 | ||||
10. | ALA5271471 | 6 | CL | = | 20 | ml/min.kg | ALA5248076 | mL.min-1.kg-1 | ||||
11. | ALA5271471 | 6 | CL | = | 20 | ml/min.kg | ALA5248075 | mL.min-1.kg-1 | ||||
12. | ALA5271471 | 6 | CL | = | 13 | ml/min.kg | ALA5248074 | mL.min-1.kg-1 | ||||
13. | ALA5271471 | 6 | F | = | 30 | % | ALA5248073 | % | ||||
14. | ALA5271471 | 6 | F | = | 100 | % | ALA5248072 | % | ||||
15. | ALA5271471 | 6 | F | = | 62 | % | ALA5248071 | % | ||||
16. | ALA5271471 | 6 | Fu | = | 1.8 | % | ALA5248065 | |||||
17. | ALA5271471 | 6 | IC50 | > | 16 | uM | ALA5248064 | nM | ||||
18. | ALA5271471 | 6 | IC50 | > | 16 | uM | ALA5248063 | nM | Homo sapiens | |||
19. | ALA5271471 | 6 | IC50 | = | 10 | uM | ALA5248062 | 5.00 | nM | Homo sapiens | ||
20. | ALA5271471 | 6 | IC50 | = | 3.6 | uM | ALA5248058 | 5.44 | nM | Homo sapiens |