# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5272415 | 8b | Drugexcretion | = | 37 | % | ALA5251575 | % | ||||
2. | ALA5272415 | 8b | CL free | = | 64 | ml/min.kg | ALA5251574 | mL.min-1.kg-1 | ||||
3. | ALA5272415 | 8b | CL | = | 19 | ml/min.kg | ALA5251573 | mL.min-1.kg-1 | ||||
4. | ALA5272415 | 8b | CL free | = | 311 | ml/min.kg | ALA5251572 | mL.min-1.kg-1 | ||||
5. | ALA5272415 | 8b | CL | = | 14 | ml/min.kg | ALA5251571 | mL.min-1.kg-1 | ||||
6. | ALA5272415 | 8b | CLH | < | 2 | microL/min/mg | ALA5251570 | mL.min-1.g-1 | ||||
7. | ALA5272415 | 8b | CLH | = | 3.2 | microL/min/mg | ALA5251569 | mL.min-1.g-1 | ||||
8. | ALA5272415 | 8b | CLH | < | 2 | microL/min/mg | ALA5251568 | mL.min-1.g-1 | ||||
9. | ALA5272415 | 8b | CLH | < | 10 | microL/min/mg | ALA5251567 | mL.min-1.g-1 | ||||
10. | ALA5272415 | 8b | CLH | = | 13 | microL/min/mg | ALA5251566 | mL.min-1.g-1 | ||||
11. | ALA5272415 | 8b | Fu | = | 30 | % | ALA5251565 | |||||
12. | ALA5272415 | 8b | Fu | = | 4.5 | % | ALA5251564 | |||||
13. | ALA5272415 | 8b | Fu | = | 15 | % | ALA5251563 | |||||
14. | ALA5272415 | 8b | logD | = | 2.8 | ALA5251562 | ||||||
15. | ALA5272415 | 8b | CLH | = | 0.33 | microL/min/mg | ALA5251561 | mL.min-1.g-1 | Homo sapiens | |||
16. | ALA5272415 | 8b | CLH | = | 0.09 | microL/min/mg | ALA5251560 | mL.min-1.g-1 | Homo sapiens | |||
17. | ALA5272415 | 8b | CLH | < | 10 | microL/min/mg | ALA5251559 | mL.min-1.g-1 | ||||
18. | ALA5272415 | 8b | IC50 | = | 9.8 | nM | ALA5251558 | 8.01 | nM | Homo sapiens | ||
19. | ALA5272415 | 8b | IC50 | = | 44.9 | nM | ALA5251557 | 7.35 | nM | Homo sapiens |