# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5272558 | 8; JMV7061 | INH | = | 57 | % | ALA5239275 | % | ||||
2. | ALA5272558 | 8; JMV7061 | INH | <= | 100 | % | ALA5239271 | % | Homo sapiens | |||
3. | ALA5272558 | 8; JMV7061 | INH | = | 51 | % | ALA5239270 | % | Mus musculus | |||
4. | ALA5272558 | 8; JMV7061 | IC50 | = | 30 | uM | ALA5239269 | 4.52 | nM | Sus scrofa | ||
5. | ALA5272558 | 8; JMV7061 | IC50 | = | 20 | uM | ALA5239266 | 4.70 | nM | Homo sapiens | ||
6. | ALA5272558 | 8; JMV7061 | PPB | = | 67.6 | % | ALA5239264 | % | ||||
7. | ALA5272558 | 8; JMV7061 | Stability | 0 | ALA5239263 | Stable | % | |||||
8. | ALA5272558 | 8; JMV7061 | t1/2 | > | 40 | min | ALA5239262 | hr | ||||
9. | ALA5272558 | 8; JMV7061 | t1/2 | > | 6 | hr | ALA5239261 | hr | ||||
10. | ALA5272558 | 8; JMV7061 | logD | = | -2.117 | ALA5239260 | ||||||
11. | ALA5272558 | 8; JMV7061 | solubility | >= | 200 | uM | ALA5239259 | nM | ||||
12. | ALA5272558 | 8; JMV7061 | CC50 | > | 250 | uM | ALA5239258 | nM | Homo sapiens | |||
13. | ALA5272558 | 8; JMV7061 | MIC | = | 64 | ug ml-1 | ALA5239257 | ug.mL-1 | Escherichia coli | |||
14. | ALA5272558 | 8; JMV7061 | MIC | = | 64 | ug ml-1 | ALA5239256 | ug.mL-1 | Escherichia coli | |||
15. | ALA5272558 | 8; JMV7061 | MIC | = | 64 | ug ml-1 | ALA5239255 | ug.mL-1 | Escherichia coli | |||
16. | ALA5272558 | 8; JMV7061 | MIC | = | 32 | ug ml-1 | ALA5239254 | ug.mL-1 | Escherichia coli | |||
17. | ALA5272558 | 8; JMV7061 | MIC | = | 32 | ug ml-1 | ALA5239253 | ug.mL-1 | Escherichia coli | |||
18. | ALA5272558 | 8; JMV7061 | MIC | = | 0.06 | ug ml-1 | ALA5239252 | ug.mL-1 | Escherichia coli | |||
19. | ALA5272558 | 8; JMV7061 | MIC | = | 0.03 | ug ml-1 | ALA5239251 | ug.mL-1 | Escherichia coli | |||
20. | ALA5272558 | 8; JMV7061 | MIC | = | 16 | ug ml-1 | ALA5239250 | ug.mL-1 | Klebsiella pneumoniae |