Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5274338	2e	Activity		0		ALA5251096		Non-Toxic
2.	ALA5274338	2e	Activity	=	68.4	%	ALA5251095			%	Homo sapiens
3.	ALA5274338	2e	Activity	=	83.5	%	ALA5251094			%	Homo sapiens
4.	ALA5274338	2e	Activity		0		ALA5251093		Active		Homo sapiens
5.	ALA5274338	2e	Activity		0		ALA5251092		Active		Homo sapiens
6.	ALA5274338	2e	Activity		0		ALA5251091		Dose-Dependent Effect		Homo sapiens
7.	ALA5274338	2e	IC50	=	6.1	nM	ALA5251090	8.21		nM	Homo sapiens
8.	ALA5274338	2e	F	=	20.4	%	ALA5251089			%
9.	ALA5274338	2e	CL	=	195	L/hr/kg	ALA5251088			mL.min-1.kg-1
10.	ALA5274338	2e	t1/2	=	0.625	hr	ALA5251087			hr
11.	ALA5274338	2e	t1/2	=	0.932	hr	ALA5251086			hr
12.	ALA5274338	2e	MRT	=	0.252	hr	ALA5251085			hr
13.	ALA5274338	2e	MRT	=	1.16	hr	ALA5251084			hr
14.	ALA5274338	2e	AUC	=	116	ng/mL.hr	ALA5251083			ng.hr.mL-1
15.	ALA5274338	2e	AUC	=	75.4	ng/mL.hr	ALA5251082			ng.hr.mL-1
16.	ALA5274338	2e	AUCt	=	115	ng/mL.hr	ALA5251081			ng.hr.mL-1
17.	ALA5274338	2e	AUCt	=	70.2	ng/mL.hr	ALA5251080			ng.hr.mL-1
18.	ALA5274338	2e	Cmax	=	174	ng/ml	ALA5251079		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
19.	ALA5274338	2e	Tmax	=	0.25	hr	ALA5251078			hr
20.	ALA5274338	2e	IC50	>	10	uM	ALA5251077			nM	Mus musculus