# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5274518 | 42; PA1103, SAR116242 | MIC | = | 47.2 | nM | ALA5241769 | nM | Plasmodium falciparum | |||
2. | ALA5274518 | 42; PA1103, SAR116242 | IC99 | = | 44.8 | nM | ALA5241769 | nM | Plasmodium falciparum | |||
3. | ALA5274518 | 42; PA1103, SAR116242 | IC90 | = | 29.3 | nM | ALA5241769 | nM | Plasmodium falciparum | |||
4. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 19.8 | nM | ALA5241769 | 7.70 | nM | Plasmodium falciparum | ||
5. | ALA5274518 | 42; PA1103, SAR116242 | Activity | = | 96 | % | ALA5241768 | % | Plasmodium falciparum | |||
6. | ALA5274518 | 42; PA1103, SAR116242 | Activity | = | 100 | % | ALA5241767 | % | Plasmodium falciparum | |||
7. | ALA5274518 | 42; PA1103, SAR116242 | Activity | = | 77 | % | ALA5241766 | % | Plasmodium falciparum | |||
8. | ALA5274518 | 42; PA1103, SAR116242 | Activity | 0 | ALA5241765 | Not Determined | Plasmodium falciparum | |||||
9. | ALA5274518 | 42; PA1103, SAR116242 | ED100 | = | 32 | mg/kg/day | ALA5241764 | mg/kg/day | Plasmodium vinckei petteri | |||
10. | ALA5274518 | 42; PA1103, SAR116242 | ED100 | = | 30 | mg/kg/day | ALA5241763 | mg/kg/day | Plasmodium vinckei | |||
11. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 13 | nM | ALA5241762 | 7.89 | nM | Plasmodium falciparum | ||
12. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 7 | nM | ALA5241761 | 8.15 | nM | Plasmodium falciparum | ||
13. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 10 | nM | ALA5241760 | 8.00 | nM | Plasmodium falciparum | ||
14. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 15 | nM | ALA5241759 | 7.82 | nM | Plasmodium falciparum | ||
15. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 15 | nM | ALA5241758 | 7.82 | nM | Plasmodium falciparum | ||
16. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 12 | nM | ALA5241757 | 7.92 | nM | Plasmodium falciparum | ||
17. | ALA5274518 | 42; PA1103, SAR116242 | IC50 | = | 24 | nM | ALA5241756 | 7.62 | nM | Plasmodium falciparum |