# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5274528 | 12 | IC50 | = | 0.063 | uM | ALA5236886 | 7.20 | nM | Homo sapiens | ||
2. | ALA5274528 | 12 | IC50 | = | 0.028 | uM | ALA5236885 | 7.55 | nM | Homo sapiens | ||
3. | ALA5274528 | 12 | Stability | < | 0.1 | % | ALA5236884 | % | ||||
4. | ALA5274528 | 12 | Stability | = | 100 | % | ALA5236883 | % | ||||
5. | ALA5274528 | 12 | CLH | = | 69 | ml/min.kg | ALA5236881 | mL.min-1.kg-1 | ||||
6. | ALA5274528 | 12 | CLH | = | 21 | ml/min.kg | ALA5236880 | mL.min-1.kg-1 | ||||
7. | ALA5274528 | 12 | Ratio | = | 0.8 | ALA5236879 | ||||||
8. | ALA5274528 | 12 | Papp | = | 13 | 10^-6 cm/s | ALA5236878 | 10^-6 cm/s | ||||
9. | ALA5274528 | 12 | IC50 | = | 1852 | nM | ALA5236877 | 5.73 | nM | Homo sapiens | ||
10. | ALA5274528 | 12 | IC50 | = | 86 | nM | ALA5236876 | 7.07 | nM | Homo sapiens |