# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5274631 | 37 | CLH | = | 37.2 | ml/min.kg | ALA5238221 | mL.min-1.kg-1 | ||||
2. | ALA5274631 | 37 | t1/2 | = | 67.4 | min | ALA5238220 | hr | ||||
3. | ALA5274631 | 37 | Kel | = | 0.25 | /hr | ALA5238219 | /hr | ||||
4. | ALA5274631 | 37 | MRT | = | 4.19 | hr | ALA5238218 | hr | ||||
5. | ALA5274631 | 37 | AUC | = | 9900 | ng.hr/ml | ALA5238217 | ng.hr.mL-1 | ||||
6. | ALA5274631 | 37 | Cmax | = | 1550 | ng/ml | ALA5238216 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
7. | ALA5274631 | 37 | Tmax | = | 3.67 | hr | ALA5238215 | hr | ||||
8. | ALA5274631 | 37 | t1/2 | = | 11.4 | hr | ALA5238214 | hr | ||||
9. | ALA5274631 | 37 | IC50 | = | 2.2 | uM | ALA5238213 | 5.66 | nM | Homo sapiens | ||
10. | ALA5274631 | 37 | IC50 | > | 100 | uM | ALA5238212 | nM | Homo sapiens | |||
11. | ALA5274631 | 37 | IC50 | = | 5.5 | uM | ALA5238211 | 5.26 | nM | Homo sapiens | ||
12. | ALA5274631 | 37 | IC50 | = | 79 | uM | ALA5238210 | 4.10 | nM | Homo sapiens | ||
13. | ALA5274631 | 37 | IC50 | = | 19 | uM | ALA5238209 | 4.72 | nM | Homo sapiens | ||
14. | ALA5274631 | 37 | IC50 | = | 37 | uM | ALA5238208 | 4.43 | nM | Homo sapiens | ||
15. | ALA5274631 | 37 | IC50 | = | 194 | uM | ALA5238207 | nM | Homo sapiens | |||
16. | ALA5274631 | 37 | CLH | = | 209 | ml/min.kg | ALA5238206 | mL.min-1.kg-1 | ||||
17. | ALA5274631 | 37 | t1/2 | = | 26.2 | min | ALA5238205 | hr | ||||
18. | ALA5274631 | 37 | Activity | 0 | ALA5238204 | Non-Toxic | ||||||
19. | ALA5274631 | 37 | Activity | = | 49 | % | ALA5238203 | % | Homo sapiens | |||
20. | ALA5274631 | 37 | Activity | = | 71 | % | ALA5238202 | % | Homo sapiens |