| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5275343 | 21a | INH | 0 | ALA5233428 | Active | % | Homo sapiens | ||||
| 2. | ALA5275343 | 21a | IC50 | = | 3.53 | uM | ALA5233415 | 5.45 | nM | Homo sapiens | ||
| 3. | ALA5275343 | 21a | IC50 | = | 8.01 | uM | ALA5233414 | 5.10 | nM | Homo sapiens | ||
| 4. | ALA5275343 | 21a | IC50 | > | 25 | uM | ALA5233413 | nM | Homo sapiens | |||
| 5. | ALA5275343 | 21a | IC50 | > | 25 | uM | ALA5233412 | nM | Homo sapiens | |||
| 6. | ALA5275343 | 21a | IC50 | > | 25 | uM | ALA5233411 | nM | Homo sapiens | |||
| 7. | ALA5275343 | 21a | IC50 | > | 25 | uM | ALA5233410 | nM | Homo sapiens | |||
| 8. | ALA5275343 | 21a | MRT | = | 1.91 | hr | ALA5233409 | hr | ||||
| 9. | ALA5275343 | 21a | AUC | = | 384 | ng.hr/ml | ALA5233408 | ng.hr.mL-1 | ||||
| 10. | ALA5275343 | 21a | Tmax | = | 0.25 | hr | ALA5233407 | hr | ||||
| 11. | ALA5275343 | 21a | t1/2 | = | 1.7 | hr | ALA5233406 | hr | ||||
| 12. | ALA5275343 | 21a | Cmax | = | 271 | ng/ml | ALA5233405 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA5275343 | 21a | CLH | = | 25.8 | ml/min.g | ALA5233404 | ml/min.g | ||||
| 14. | ALA5275343 | 21a | CLH | = | 18.2 | ml/min.g | ALA5233403 | ml/min.g | ||||
| 15. | ALA5275343 | 21a | CLH | = | 14.5 | ml/min.g | ALA5233402 | ml/min.g | ||||
| 16. | ALA5275343 | 21a | t1/2 | = | 81.3 | min | ALA5233401 | hr | ||||
| 17. | ALA5275343 | 21a | t1/2 | = | 116 | min | ALA5233400 | hr | ||||
| 18. | ALA5275343 | 21a | t1/2 | = | 145 | min | ALA5233399 | hr | ||||
| 19. | ALA5275343 | 21a | IC50 | = | 2.35 | uM | ALA5233398 | 5.63 | nM | Homo sapiens | ||
| 20. | ALA5275343 | 21a | Activity | 0 | ALA5233396 | Active | Rattus norvegicus |
The page will load shortly, Thanks for your patience!