| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5275403 | 16 | IC50 | = | 17 | nM | ALA5226008 | 7.77 | nM | |||
| 2. | ALA5275403 | 16 | IC50 | = | 1.7 | nM | ALA5226007 | 8.77 | nM | Homo sapiens | ||
| 3. | ALA5275403 | 16 | INH | 0 | ALA5226007 | Dose-Dependent Effect | % | Homo sapiens | ||||
| 4. | ALA5275403 | 16 | Activity | 0 | ALA5226004 | Dose-Dependent Effect | ||||||
| 5. | ALA5275403 | 16 | Activity | = | 20 | % | ALA5226003 | % | ||||
| 6. | ALA5275403 | 16 | F | = | 48 | % | ALA5226002 | % | ||||
| 7. | ALA5275403 | 16 | t1/2 | = | 8.2 | hr | ALA5226001 | hr | ||||
| 8. | ALA5275403 | 16 | fVdss | = | 49 | L/Kg | ALA5226000 | L/Kg | ||||
| 9. | ALA5275403 | 16 | CL | = | 75 | ml/min.kg | ALA5225999 | mL.min-1.kg-1 | ||||
| 10. | ALA5275403 | 16 | CL | = | 12 | ml/min.kg | ALA5225998 | mL.min-1.kg-1 | ||||
| 11. | ALA5275403 | 16 | F | = | 95 | % | ALA5225997 | % | ||||
| 12. | ALA5275403 | 16 | t1/2 | = | 3.4 | hr | ALA5225996 | hr | ||||
| 13. | ALA5275403 | 16 | fVdss | = | 16 | L/Kg | ALA5225995 | L/Kg | ||||
| 14. | ALA5275403 | 16 | CL | = | 55 | ml/min.kg | ALA5225994 | mL.min-1.kg-1 | ||||
| 15. | ALA5275403 | 16 | CL | = | 6.1 | ml/min.kg | ALA5225993 | mL.min-1.kg-1 | ||||
| 16. | ALA5275403 | 16 | IC50 | = | 2.2 | uM | ALA5225992 | 5.66 | nM | Homo sapiens | ||
| 17. | ALA5275403 | 16 | IC50 | = | 10.2 | uM | ALA5225991 | 4.99 | nM | Homo sapiens | ||
| 18. | ALA5275403 | 16 | IC50 | = | 4.1 | uM | ALA5225990 | 5.39 | nM | Homo sapiens | ||
| 19. | ALA5275403 | 16 | Emax | = | 26 | % | ALA5225989 | % | ||||
| 20. | ALA5275403 | 16 | EC50 | > | 30 | uM | ALA5225988 | nM | Homo sapiens |
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