| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5276605 | 24 | F | = | 3 | % | ALA5225692 | % | ||||
| 2. | ALA5276605 | 24 | Cmax | = | 109 | ng/ml | ALA5225691 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 3. | ALA5276605 | 24 | AUC | = | 632 | ng.hr/ml | ALA5225690 | ng.hr.mL-1 | ||||
| 4. | ALA5276605 | 24 | Vdss | = | 1.4 | L/Kg | ALA5225689 | L.kg-1 | ||||
| 5. | ALA5276605 | 24 | CL | = | 8.5 | ml/min.kg | ALA5225688 | mL.min-1.kg-1 | ||||
| 6. | ALA5276605 | 24 | t1/2 | = | 2.7 | hr | ALA5225687 | hr | ||||
| 7. | ALA5276605 | 24 | INH | 0 | ALA5225686 | Not Active | % | Homo sapiens | ||||
| 8. | ALA5276605 | 24 | INH | 0 | ALA5225685 | Not Active | % | Homo sapiens | ||||
| 9. | ALA5276605 | 24 | INH | 0 | ALA5225684 | Not Active | % | Homo sapiens | ||||
| 10. | ALA5276605 | 24 | INH | 0 | ALA5225683 | Not Active | % | Homo sapiens | ||||
| 11. | ALA5276605 | 24 | pIC50 | = | 5 | ALA5225682 | 5.00 | nM | Homo sapiens | |||
| 12. | ALA5276605 | 24 | pIC50 | < | 5 | ALA5225681 | nM | Homo sapiens | ||||
| 13. | ALA5276605 | 24 | pIC50 | = | 5.4 | ALA5225680 | 5.40 | nM | Homo sapiens | |||
| 14. | ALA5276605 | 24 | pIC50 | = | 5.2 | ALA5225679 | 5.20 | nM | Homo sapiens | |||
| 15. | ALA5276605 | 24 | t1/2 | = | 116 | min | ALA5225677 | hr | ||||
| 16. | ALA5276605 | 24 | t1/2 | = | 87 | min | ALA5225676 | hr | ||||
| 17. | ALA5276605 | 24 | pIC50 | = | 5 | ALA5225675 | 5.00 | nM | Homo sapiens | |||
| 18. | ALA5276605 | 24 | Selectivity ratio | > | 1000 | ALA5225674 | ||||||
| 19. | ALA5276605 | 24 | Selectivity ratio | > | 1000 | ALA5225673 | ||||||
| 20. | ALA5276605 | 24 | Selectivity ratio | > | 1000 | ALA5225672 |
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