Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5276988	37	Activity		0		ALA5244162		Dose-Dependent Effect		Mus musculus
2.	ALA5276988	37	F	=	39.9	%	ALA5244161			%
3.	ALA5276988	37	Tmax	=	2	hr	ALA5244160			hr
4.	ALA5276988	37	t1/2	=	4.82	hr	ALA5244159			hr
5.	ALA5276988	37	AUC	=	4449	hr.ng/ml	ALA5244158			ng.hr.mL-1
6.	ALA5276988	37	Cmax	=	560	ng/ml	ALA5244157		standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
7.	ALA5276988	37	CL	=	180	ml/hr/kg	ALA5244156			mL.min-1.kg-1
8.	ALA5276988	37	t1/2	=	3.37	hr	ALA5244155			hr
9.	ALA5276988	37	AUC	=	5569	hr.ng/ml	ALA5244154			ng.hr.mL-1
10.	ALA5276988	37	Drug uptake	=	1920	ng/mg	ALA5244153			ng/mg
11.	ALA5276988	37	Papp	=	3	10^-6 cm/s	ALA5244152			10^-6 cm/s
12.	ALA5276988	37	IC50	=	0.093	uM	ALA5244151	7.03		nM	Homo sapiens
13.	ALA5276988	37	CLH	=	0.004	ml/min.kg	ALA5244150			mL.min-1.kg-1
14.	ALA5276988	37	IC50	=	1.401	uM	ALA5244149	5.85		nM
15.	ALA5276988	37	CLH	=	0.011	ml/min.kg	ALA5244148			mL.min-1.kg-1
16.	ALA5276988	37	INH		0		ALA5244147		Dose-Dependent Effect	%	Homo sapiens