# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5277056 | 1g; T-914 | logD | = | 1.62 | ALA5228518 | ||||||
2. | ALA5277056 | 1g; T-914 | Ratio | = | 0.277 | ALA5228517 | ||||||
3. | ALA5277056 | 1g; T-914 | Ratio | = | 0.67 | ALA5228516 | ||||||
4. | ALA5277056 | 1g; T-914 | Ratio | = | 0.69 | ALA5228515 | ||||||
5. | ALA5277056 | 1g; T-914 | Vdss | = | 3132 | ml/kg | ALA5228514 | L.kg-1 | ||||
6. | ALA5277056 | 1g; T-914 | CL | = | 1948 | ml/hr/kg | ALA5228513 | mL.min-1.kg-1 | ||||
7. | ALA5277056 | 1g; T-914 | t1/2 | = | 1.75 | hr | ALA5228512 | hr | ||||
8. | ALA5277056 | 1g; T-914 | AUC | = | 51.6 | ng.hr/ml | ALA5228511 | ng.hr.mL-1 | ||||
9. | ALA5277056 | 1g; T-914 | Cp | = | 31.2 | ng/ml | ALA5228510 | ng/ml | ||||
10. | ALA5277056 | 1g; T-914 | IC50 | = | 33 | uM | ALA5228509 | 4.48 | nM | Homo sapiens | ||
11. | ALA5277056 | 1g; T-914 | IC50 | > | 100 | uM | ALA5228508 | nM | Homo sapiens | |||
12. | ALA5277056 | 1g; T-914 | Activity | 0 | ALA5228507 | Active | Homo sapiens | |||||
13. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228506 | Metabolite_Notdetected | ||||||
14. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228505 | Metabolite_Detected | ||||||
15. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228504 | Metabolite_Notdetected | ||||||
16. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228503 | Metabolite_Notdetected | ||||||
17. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228502 | Metabolite_Notdetected | ||||||
18. | ALA5277056 | 1g; T-914 | Drug metabolism | 0 | ALA5228501 | Metabolite_Notdetected | ||||||
19. | ALA5277056 | 1g; T-914 | Retention_time | = | 11.85 | min | ALA5228500 | min | ||||
20. | ALA5277056 | 1g; T-914 | Drug metabolism | = | 0.21 | nmol/g | ALA5228499 | nmol/g |