# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5277468 | 23 | Ratio IC50 | = | 2.1 | ALA5239179 | ||||||
2. | ALA5277468 | 23 | IC50 | = | 53 | nM | ALA5239178 | 7.28 | nM | Mus musculus | ||
3. | ALA5277468 | 23 | IC50 | = | 113 | nM | ALA5239177 | 6.95 | nM | Mus musculus | ||
4. | ALA5277468 | 23 | Ratio IC50 | = | 0.5 | ALA5239176 | ||||||
5. | ALA5277468 | 23 | IC50 | = | 77 | nM | ALA5239175 | 7.11 | nM | |||
6. | ALA5277468 | 23 | IC50 | = | 35 | nM | ALA5239174 | 7.46 | nM | Rattus norvegicus | ||
7. | ALA5277468 | 23 | Ratio IC50 | = | 5.8 | ALA5239173 | ||||||
8. | ALA5277468 | 23 | IC50 | = | 42 | nM | ALA5239172 | 7.38 | nM | Homo sapiens | ||
9. | ALA5277468 | 23 | IC50 | = | 242 | nM | ALA5239171 | 6.62 | nM | Homo sapiens | ||
10. | ALA5277468 | 23 | F | = | 32 | % | ALA5239163 | % | ||||
11. | ALA5277468 | 23 | AUCt | = | 3.53 | uM.hr | ALA5239162 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
12. | ALA5277468 | 23 | Cmax | = | 0.9 | uM | ALA5239161 | nM | ||||
13. | ALA5277468 | 23 | CLH | = | 27 | uL/min | ALA5239160 | uL/min | ||||
14. | ALA5277468 | 23 | Ratio | = | 14 | ALA5239159 | ||||||
15. | ALA5277468 | 23 | Papp | = | 1.9 | 10^-6 cm/s | ALA5239158 | 10^-6 cm/s | ||||
16. | ALA5277468 | 23 | IC50 | = | 233 | uM | ALA5239155 | nM | Homo sapiens | |||
17. | ALA5277468 | 23 | IC50 | = | 69 | uM | ALA5239154 | 4.16 | nM | Homo sapiens |