# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5278011 | 10 | IC50 | = | 4.2 | uM | ALA5226275 | 5.38 | nM | Homo sapiens | ||
2. | ALA5278011 | 10 | F | = | 7 | % | ALA5226274 | % | ||||
3. | ALA5278011 | 10 | t1/2 | > | 4 | hr | ALA5226273 | hr | ||||
4. | ALA5278011 | 10 | Vdss | = | 1.8 | L/Kg | ALA5226272 | L.kg-1 | ||||
5. | ALA5278011 | 10 | CL | = | 14 | ml/min.Kg | ALA5226271 | mL.min-1.kg-1 | ||||
6. | ALA5278011 | 10 | Vdss | = | 1.9 | L/Kg | ALA5226270 | L.kg-1 | ||||
7. | ALA5278011 | 10 | CL | = | 17 | ml/min.Kg | ALA5226269 | mL.min-1.kg-1 | ||||
8. | ALA5278011 | 10 | t1/2 | > | 2.3 | hr | ALA5226268 | hr | ||||
9. | ALA5278011 | 10 | Papp | = | 0.02 | 10^-6 cm/s | ALA5226263 | 10^-6 cm/s | ||||
10. | ALA5278011 | 10 | EC50 | = | 520 | nM | ALA5226256 | 6.28 | nM | Homo sapiens | ||
11. | ALA5278011 | 10 | EC50 | = | 37 | nM | ALA5226255 | 7.43 | nM | Homo sapiens | ||
12. | ALA5278011 | 10 | IC50 | = | 6 | nM | ALA5226254 | 8.22 | nM | Homo sapiens |