# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5278110 | 31 | INH | <= | 100 | % | ALA5239271 | % | Homo sapiens | |||
2. | ALA5278110 | 31 | INH | = | 42 | % | ALA5239270 | % | Mus musculus | |||
3. | ALA5278110 | 31 | INH | = | 58 | % | ALA5239268 | % | Sus scrofa | |||
4. | ALA5278110 | 31 | IC50 | = | 35 | uM | ALA5239266 | 4.46 | nM | Homo sapiens | ||
5. | ALA5278110 | 31 | Activity | = | 98.1 | % | ALA5239265 | % | ||||
6. | ALA5278110 | 31 | PPB | = | 62.3 | % | ALA5239264 | % | ||||
7. | ALA5278110 | 31 | CL | = | 5.5 | microL/min/mg | ALA5239263 | mL.min-1.g-1 | ||||
8. | ALA5278110 | 31 | t1/2 | > | 40 | min | ALA5239262 | hr | ||||
9. | ALA5278110 | 31 | t1/2 | > | 6 | hr | ALA5239261 | hr | ||||
10. | ALA5278110 | 31 | logD | = | -1.925 | ALA5239260 | ||||||
11. | ALA5278110 | 31 | solubility | >= | 200 | uM | ALA5239259 | nM | ||||
12. | ALA5278110 | 31 | CC50 | = | 105 | uM | ALA5239258 | nM | Homo sapiens | |||
13. | ALA5278110 | 31 | MIC | = | 0.06 | ug ml-1 | ALA5239236 | ug.mL-1 | Pseudomonas aeruginosa | |||
14. | ALA5278110 | 31 | MIC | = | 8 | ug ml-1 | ALA5239235 | ug.mL-1 | Pseudomonas aeruginosa | |||
15. | ALA5278110 | 31 | MIC | = | 0.03 | ug ml-1 | ALA5239234 | ug.mL-1 | Klebsiella pneumoniae | |||
16. | ALA5278110 | 31 | MIC | = | 0.06 | ug ml-1 | ALA5239233 | ug.mL-1 | Klebsiella pneumoniae | |||
17. | ALA5278110 | 31 | Ki | = | 4.5 | uM | ALA5239211 | 5.35 | nM | |||
18. | ALA5278110 | 31 | Ki | = | 0.038 | uM | ALA5239210 | 7.42 | nM | |||
19. | ALA5278110 | 31 | Ki | = | 0.42 | uM | ALA5239209 | 6.38 | nM | |||
20. | ALA5278110 | 31 | Ki | = | 0.35 | uM | ALA5239208 | 6.46 | nM |