# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5278512 | 4 | IC50 | = | 1.9 | uM | ALA5225582 | 5.72 | nM | Homo sapiens | ||
2. | ALA5278512 | 4 | IC50 | = | 94 | nM | ALA5225581 | 7.03 | nM | Homo sapiens | ||
3. | ALA5278512 | 4 | IC50 | = | 9 | nM | ALA5225580 | 8.05 | nM | Homo sapiens | ||
4. | ALA5278512 | 4 | INH | = | 51.3 | % | ALA5225579 | % | Homo sapiens | |||
5. | ALA5278512 | 4 | INH | = | 65.9 | % | ALA5225578 | % | Homo sapiens | |||
6. | ALA5278512 | 4 | INH | = | 74.6 | % | ALA5225577 | % | Homo sapiens | |||
7. | ALA5278512 | 4 | INH | = | 52.6 | % | ALA5225576 | % | Homo sapiens | |||
8. | ALA5278512 | 4 | Drug recovery | = | 19 | % | ALA5225575 | % | ||||
9. | ALA5278512 | 4 | PPB | = | 96 | % | ALA5225574 | % | ||||
10. | ALA5278512 | 4 | logD | > | 3.68 | ALA5225573 | ||||||
11. | ALA5278512 | 4 | permeability | = | 1.6 | 10^-6 cm/s | ALA5225572 | 10^-6 cm/s | ||||
12. | ALA5278512 | 4 | permeability | = | 11.3 | 10^-6 cm/s | ALA5225571 | 10^-6 cm/s | ||||
13. | ALA5278512 | 4 | solubility | = | 11.5 | uM | ALA5225570 | nM | ||||
14. | ALA5278512 | 4 | solubility | > | 200 | uM | ALA5225569 | nM | ||||
15. | ALA5278512 | 4 | solubility | = | 4 | uM | ALA5225568 | nM | ||||
16. | ALA5278512 | 4 | Activity | 0 | ALA5225566 | Not Active | ||||||
17. | ALA5278512 | 4 | IC50 | = | 0.878 | uM | ALA5225565 | 6.06 | nM | Homo sapiens | ||
18. | ALA5278512 | 4 | IC50 | = | 1.92 | uM | ALA5225564 | 5.72 | nM | Homo sapiens | ||
19. | ALA5278512 | 4 | t1/2 | > | 60 | min | ALA5225563 | hr |