# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5278656 | 19 | INH | 0 | ALA5239811 | Active | % | Homo sapiens | ||||
2. | ALA5278656 | 19 | INH | 0 | ALA5239810 | Active | % | |||||
3. | ALA5278656 | 19 | INH | 0 | ALA5239809 | Active | % | |||||
4. | ALA5278656 | 19 | Activity | < | 5 | % | ALA5239808 | % | ||||
5. | ALA5278656 | 19 | INH | = | 63 | % | ALA5239807 | % | Homo sapiens | |||
6. | ALA5278656 | 19 | TGI | = | 81 | % | ALA5239806 | % | Homo sapiens | |||
7. | ALA5278656 | 19 | INH | 0 | ALA5239805 | Dose-Dependent Effect | % | Mus musculus | ||||
8. | ALA5278656 | 19 | INH | 0 | ALA5239804 | Dose-Dependent Effect | % | Mus musculus | ||||
9. | ALA5278656 | 19 | INH | 0 | ALA5239803 | Dose-Dependent Effect | % | Mus musculus | ||||
10. | ALA5278656 | 19 | IC50 | = | 6 | nM | ALA5239802 | 8.22 | nM | |||
11. | ALA5278656 | 19 | IC50 | = | 24.6 | nM | ALA5239801 | 7.61 | nM | Homo sapiens | ||
12. | ALA5278656 | 19 | IC50 | = | 29.6 | nM | ALA5239800 | 7.53 | nM | Homo sapiens | ||
13. | ALA5278656 | 19 | IC50 | = | 46.7 | nM | ALA5239799 | 7.33 | nM | Homo sapiens | ||
14. | ALA5278656 | 19 | IC50 | = | 64.3 | nM | ALA5239798 | 7.19 | nM | Homo sapiens | ||
15. | ALA5278656 | 19 | F | = | 61.5 | % | ALA5239797 | % | ||||
16. | ALA5278656 | 19 | MRT | = | 3.87 | hr | ALA5239796 | hr | ||||
17. | ALA5278656 | 19 | AUC | = | 1087 | hr.ng/ml | ALA5239795 | ng.hr.mL-1 | ||||
18. | ALA5278656 | 19 | AUClast | = | 965 | hr.ng/ml | ALA5239794 | ng.hr.mL-1 | ||||
19. | ALA5278656 | 19 | Cmax | = | 202 | ng/ml | ALA5239793 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
20. | ALA5278656 | 19 | Tmax | = | 2 | hr | ALA5239792 | hr |