# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5279503 | 7h | AUC | = | 792 | nM.hr | ALA5225851 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
2. | ALA5279503 | 7h | Cmax | = | 202 | nM | ALA5225850 | nM | ||||
3. | ALA5279503 | 7h | t1/2 | = | 2.5 | hr | ALA5225849 | hr | ||||
4. | ALA5279503 | 7h | Vdss | = | 11 | L/Kg | ALA5225848 | L.kg-1 | ||||
5. | ALA5279503 | 7h | QH | = | 130 | % | ALA5225847 | % | ||||
6. | ALA5279503 | 7h | CL | = | 4.16 | L/hr/kg | ALA5225846 | mL.min-1.kg-1 | ||||
7. | ALA5279503 | 7h | permeability | = | 1.3 | 10^-6 cm/s | ALA5225842 | 10^-6 cm/s | ||||
8. | ALA5279503 | 7h | INH | = | 38 | % | ALA5225841 | % | Homo sapiens | |||
9. | ALA5279503 | 7h | IC50 | = | 59 | nM | ALA5225840 | 7.23 | nM | Homo sapiens | ||
10. | ALA5279503 | 7h | IC50 | = | 192 | nM | ALA5225838 | 6.72 | nM | Homo sapiens | ||
11. | ALA5279503 | 7h | IC50 | = | 242 | nM | ALA5225837 | 6.62 | nM | Homo sapiens | ||
12. | ALA5279503 | 7h | IC50 | = | 2987 | nM | ALA5225832 | 5.53 | nM | Homo sapiens | ||
13. | ALA5279503 | 7h | Ki | = | 60 | nM | ALA5225831 | 7.22 | nM | Homo sapiens | ||
14. | ALA5279503 | 7h | Ki | < | 0.1 | nM | ALA5225830 | nM | Homo sapiens |