# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5280682 | 35b | CL | = | 5.66 | L/hr/kg | ALA5228285 | mL.min-1.kg-1 | ||||
2. | ALA5280682 | 35b | Ratio | = | 8.2 | ALA5228284 | ||||||
3. | ALA5280682 | 35b | Papp | = | 6.8 | 10^-6 cm/s | ALA5228283 | 10^-6 cm/s | ||||
4. | ALA5280682 | 35b | logD | = | 1.6 | ALA5228280 | ||||||
5. | ALA5280682 | 35b | IC50 | = | 340 | nM | ALA5228279 | 6.47 | nM | Homo sapiens | ||
6. | ALA5280682 | 35b | IC50 | = | 1.6 | nM | ALA5228278 | 8.80 | nM | Homo sapiens | ||
7. | ALA5280682 | 35b | CLH | = | 35 | microL/min/mg | ALA5228277 | mL.min-1.g-1 | ||||
8. | ALA5280682 | 35b | CLH | < | 10 | microL/min/mg | ALA5228276 | mL.min-1.g-1 | ||||
9. | ALA5280682 | 35b | solubility | = | 847 | ug ml-1 | ALA5228274 | ug.mL-1 | ||||
10. | ALA5280682 | 35b | EC50 | = | 16 | nM | ALA5228273 | 7.80 | nM | |||
11. | ALA5280682 | 35b | IC50 | = | 2.1 | nM | ALA5228272 | 8.68 | nM | Homo sapiens |