| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5282319 | 45 | Ratio | < | 1 | ALA5252073 | Homo sapiens | |||||
| 2. | ALA5282319 | 45 | F | = | 100 | % | ALA5252041 | % | ||||
| 3. | ALA5282319 | 45 | Cmax | = | 10.7 | uM | ALA5252040 | nM | ||||
| 4. | ALA5282319 | 45 | AUC | = | 47 | uM.hr | ALA5252039 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 5. | ALA5282319 | 45 | t1/2 | = | 3.1 | hr | ALA5252038 | hr | ||||
| 6. | ALA5282319 | 45 | MRT | = | 2.4 | hr | ALA5252037 | hr | ||||
| 7. | ALA5282319 | 45 | Vdss | = | 1.5 | L/Kg | ALA5252036 | L.kg-1 | ||||
| 8. | ALA5282319 | 45 | CL | = | 10.6 | ml/min.kg | ALA5252035 | mL.min-1.kg-1 | ||||
| 9. | ALA5282319 | 45 | permeability | = | 9.9 | 10^-6 cm/s | ALA5252032 | 10^-6 cm/s | ||||
| 10. | ALA5282319 | 45 | permeability | = | 32.2 | 10^-6 cm/s | ALA5252031 | 10^-6 cm/s | ||||
| 11. | ALA5282319 | 45 | permeability | = | 29.8 | 10^-6 cm/s | ALA5252030 | 10^-6 cm/s | ||||
| 12. | ALA5282319 | 45 | permeability | = | 7.8 | 10^-6 cm/s | ALA5252029 | 10^-6 cm/s | ||||
| 13. | ALA5282319 | 45 | Fu | = | 1.2 | % | ALA5252028 | |||||
| 14. | ALA5282319 | 45 | Fu | = | 1 | % | ALA5252027 | |||||
| 15. | ALA5282319 | 45 | Stability | = | 9 | % | ALA5252024 | % | ||||
| 16. | ALA5282319 | 45 | Stability | = | 31 | % | ALA5252023 | % | ||||
| 17. | ALA5282319 | 45 | IC50 | = | 36 | nM | ALA5252014 | 7.44 | nM | Homo sapiens | ||
| 18. | ALA5282319 | 45 | IC50 | = | 0.21 | nM | ALA5252013 | 9.68 | nM | Homo sapiens | ||
| 19. | ALA5282319 | 45 | IC50 | = | 0.42 | nM | ALA5252012 | 9.38 | nM |
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