# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5282583 | 13 | solubility | < | 2 | uM | ALA5239710 | nM | ||||
2. | ALA5282583 | 13 | MRT | = | 1.2 | hr | ALA5239705 | hr | ||||
3. | ALA5282583 | 13 | CL free | = | 5400 | ml/min.Kg | ALA5239704 | mL.min-1.kg-1 | ||||
4. | ALA5282583 | 13 | CL | = | 11 | ml/min.Kg | ALA5239703 | mL.min-1.kg-1 | ||||
5. | ALA5282583 | 13 | F | = | 108 | % | ALA5239698 | % | ||||
6. | ALA5282583 | 13 | MRT | = | 1 | hr | ALA5239697 | hr | ||||
7. | ALA5282583 | 13 | CL free | = | 2300 | ml/min.Kg | ALA5239696 | mL.min-1.kg-1 | ||||
8. | ALA5282583 | 13 | CL | = | 17 | ml/min.Kg | ALA5239695 | mL.min-1.kg-1 | ||||
9. | ALA5282583 | 13 | F | = | 83 | % | ALA5239683 | % | ||||
10. | ALA5282583 | 13 | MRT | = | 3.8 | hr | ALA5239682 | hr | ||||
11. | ALA5282583 | 13 | CL free | = | 471 | ml/min.Kg | ALA5239681 | mL.min-1.kg-1 | ||||
12. | ALA5282583 | 13 | CL | = | 3.4 | ml/min.Kg | ALA5239680 | mL.min-1.kg-1 | ||||
13. | ALA5282583 | 13 | Papp | = | 31 | 10^-6 cm/s | ALA5239658 | 10^-6 cm/s | ||||
14. | ALA5282583 | 13 | Ratio | = | 5.6 | ALA5239657 | ||||||
15. | ALA5282583 | 13 | IC50 | = | 18 | nM | ALA5239656 | 7.75 | nM | Homo sapiens | ||
16. | ALA5282583 | 13 | IC50 | = | 6 | nM | ALA5239655 | 8.22 | nM | Homo sapiens |