# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5284433 | 7i | AUC | = | 1110 | nM.hr | ALA5225851 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
2. | ALA5284433 | 7i | Cmax | = | 277 | nM | ALA5225850 | nM | ||||
3. | ALA5284433 | 7i | t1/2 | = | 1.7 | hr | ALA5225849 | hr | ||||
4. | ALA5284433 | 7i | Vdss | = | 9.3 | L/Kg | ALA5225848 | L.kg-1 | ||||
5. | ALA5284433 | 7i | QH | = | 160 | % | ALA5225847 | % | ||||
6. | ALA5284433 | 7i | CL | = | 5.2 | L/hr/kg | ALA5225846 | mL.min-1.kg-1 | ||||
7. | ALA5284433 | 7i | permeability | = | 0.9 | 10^-6 cm/s | ALA5225842 | 10^-6 cm/s | ||||
8. | ALA5284433 | 7i | INH | = | 67 | % | ALA5225841 | % | Homo sapiens | |||
9. | ALA5284433 | 7i | IC50 | = | 373 | nM | ALA5225840 | 6.43 | nM | Homo sapiens | ||
10. | ALA5284433 | 7i | IC50 | = | 1479 | nM | ALA5225838 | 5.83 | nM | Homo sapiens | ||
11. | ALA5284433 | 7i | IC50 | = | 464 | nM | ALA5225837 | 6.33 | nM | Homo sapiens | ||
12. | ALA5284433 | 7i | IC50 | = | 2557 | nM | ALA5225832 | 5.59 | nM | Homo sapiens | ||
13. | ALA5284433 | 7i | Ki | = | 232 | nM | ALA5225831 | 6.63 | nM | Homo sapiens | ||
14. | ALA5284433 | 7i | Ki | = | 2 | nM | ALA5225830 | 8.70 | nM | Homo sapiens |