| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5284493 | 25 | FC | = | 4.6 | ALA5260323 | Rattus norvegicus | |||||
| 2. | ALA5284493 | 25 | INH | 0 | ALA5260322 | Dose-Dependent Effect | % | Rattus norvegicus | ||||
| 3. | ALA5284493 | 25 | F | = | 136 | % | ALA5260321 | % | ||||
| 4. | ALA5284493 | 25 | AUC | = | 324 | uM.hr | ALA5260320 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 5. | ALA5284493 | 25 | AUC | = | 79 | uM.hr | ALA5260319 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 6. | ALA5284493 | 25 | Vd | = | 0.18 | L/Kg | ALA5260318 | L.kg-1 | ||||
| 7. | ALA5284493 | 25 | CL | = | 0.03 | L/hr/kg | ALA5260317 | mL.min-1.kg-1 | ||||
| 8. | ALA5284493 | 25 | Tmax | = | 1.3 | hr | ALA5260316 | hr | ||||
| 9. | ALA5284493 | 25 | t1/2 | = | 4.5 | hr | ALA5260315 | hr | ||||
| 10. | ALA5284493 | 25 | MRT | = | 10 | hr | ALA5260314 | hr | ||||
| 11. | ALA5284493 | 25 | MRT | = | 5.6 | hr | ALA5260313 | hr | ||||
| 12. | ALA5284493 | 25 | -TdeltaS | = | -1.2 | kcal/mol | ALA5260312 | kcal/mol | Homo sapiens | |||
| 13. | ALA5284493 | 25 | deltaH | = | -8.2 | kcal/mol | ALA5260311 | kcal/mol | Homo sapiens | |||
| 14. | ALA5284493 | 25 | deltaG | = | -9.4 | kcal/mol | ALA5260310 | kcal/mol | Homo sapiens | |||
| 15. | ALA5284493 | 25 | IC50 | = | 2 | uM | ALA5260309 | 5.70 | nM | |||
| 16. | ALA5284493 | 25 | Stability | = | 87 | % | ALA5260308 | % | ||||
| 17. | ALA5284493 | 25 | Stability | = | 70 | % | ALA5260307 | % | ||||
| 18. | ALA5284493 | 25 | Papp | = | 33 | 10^-6 cm/s | ALA5260306 | 10^-6 cm/s | ||||
| 19. | ALA5284493 | 25 | solubility | = | 303 | uM | ALA5260305 | nM | ||||
| 20. | ALA5284493 | 25 | solubility | >= | 475 | uM | ALA5260304 | nM |
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