| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5286257 | 7o | BPR | = | 0.4 | ALA5223858 | ||||||
| 2. | ALA5286257 | 7o | CL | = | 53 | ml/min.kg | ALA5223857 | mL.min-1.kg-1 | ||||
| 3. | ALA5286257 | 7o | Vdss | = | 5.5 | L/Kg | ALA5223856 | L.kg-1 | ||||
| 4. | ALA5286257 | 7o | beta t1/2 | = | 1.2 | hr | ALA5223855 | hr | ||||
| 5. | ALA5286257 | 7o | AUC | = | 242 | ng.hr/ml | ALA5223854 | ng.hr.mL-1 | ||||
| 6. | ALA5286257 | 7o | Cmax | = | 99 | ng/ml | ALA5223853 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 7. | ALA5286257 | 7o | F | = | 26 | % | ALA5223852 | % | ||||
| 8. | ALA5286257 | 7o | INH | = | 88 | % | ALA5223848 | % | Homo sapiens | |||
| 9. | ALA5286257 | 7o | IC50 | = | 1.5 | uM | ALA5223847 | 5.82 | nM | Homo sapiens | ||
| 10. | ALA5286257 | 7o | Drug metabolism | = | 20.2 | % | ALA5223846 | % | ||||
| 11. | ALA5286257 | 7o | Drug metabolism | = | 15.6 | % | ALA5223845 | % | ||||
| 12. | ALA5286257 | 7o | Emax | = | 34 | % | ALA5223844 | % | Homo sapiens | |||
| 13. | ALA5286257 | 7o | EC50 | = | 21.6 | nM | ALA5223843 | 7.67 | nM | Homo sapiens |
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