# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5286389 | 3g.HCl | Drugexcretion | < | 3 | % | ALA5261552 | % | ||||
2. | ALA5286389 | 3g.HCl | Drugexcretion | < | 3 | % | ALA5261551 | % | ||||
3. | ALA5286389 | 3g.HCl | F | < | 3 | % | ALA5261550 | % | ||||
4. | ALA5286389 | 3g.HCl | Drugabsorption | = | 3 | % | ALA5261549 | % | ||||
5. | ALA5286389 | 3g.HCl | Drug metabolism | = | 50 | ml/min/g | ALA5261547 | ml/min/g | ||||
6. | ALA5286389 | 3g.HCl | Drug metabolism | = | 50 | ml/min/g | ALA5261546 | ml/min/g | ||||
7. | ALA5286389 | 3g.HCl | Drug metabolism | = | 25 | ml/min/g | ALA5261545 | ml/min/g | ||||
8. | ALA5286389 | 3g.HCl | Drug metabolism | = | 12 | ml/min/g | ALA5261544 | ml/min/g | ||||
9. | ALA5286389 | 3g.HCl | Drug metabolism | > | 50 | ml/min.kg | ALA5261543 | ml/min.kg | ||||
10. | ALA5286389 | 3g.HCl | Drug metabolism | = | 12 | ml/min.kg | ALA5261542 | ml/min.kg | ||||
11. | ALA5286389 | 3g.HCl | Drug metabolism | = | 11 | ml/min.kg | ALA5261541 | ml/min.kg | ||||
12. | ALA5286389 | 3g.HCl | Drug metabolism | 0 | ALA5261540 | Metabolite_Detected | ||||||
13. | ALA5286389 | 3g.HCl | IC50 | = | 27 | uM | ALA5261539 | 4.57 | nM | Homo sapiens | ||
14. | ALA5286389 | 3g.HCl | IC50 | = | 6.7 | uM | ALA5261538 | 5.17 | nM | Homo sapiens | ||
15. | ALA5286389 | 3g.HCl | IC50 | = | 1.3 | uM | ALA5261537 | 5.89 | nM | Homo sapiens | ||
16. | ALA5286389 | 3g.HCl | TDI | 0 | ALA5261535 | Not Active | Homo sapiens | |||||
17. | ALA5286389 | 3g.HCl | Activity | 0 | ALA5261534 | Active | Cavia porcellus | |||||
18. | ALA5286389 | 3g.HCl | Time | < | 48 | hr | ALA5261533 | hr | Cavia porcellus | |||
19. | ALA5286389 | 3g.HCl | pA2 | = | 8.7 | ALA5261531 | 8.70 | nM | Cavia porcellus | |||
20. | ALA5286389 | 3g.HCl | pA2 | = | 8.2 | ALA5261530 | 8.20 | nM | Homo sapiens |