Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5286829	1p	Ratio	<	0.004		ALA5252406
2.	ALA5286829	1p	F	=	65	%	ALA5252405			%
3.	ALA5286829	1p	Vdss	=	0.57	L/Kg	ALA5252404			L.kg-1
4.	ALA5286829	1p	CL	=	2.58	ml/min.kg	ALA5252403			mL.min-1.kg-1
5.	ALA5286829	1p	t1/2	=	5	hr	ALA5252402			hr
6.	ALA5286829	1p	AUC	=	12.1	uM.hr	ALA5252401		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW	ng.hr.mL-1
7.	ALA5286829	1p	Tmax	=	1	hr	ALA5252400			hr
8.	ALA5286829	1p	Cmax	=	1.7	uM	ALA5252399			nM
9.	ALA5286829	1p	Efficacy	=	79	%	ALA5252395			%	Mus musculus
10.	ALA5286829	1p	Fu	<	0.2	%	ALA5252394
11.	ALA5286829	1p	Therm_solubility	=	440	uM	ALA5252393			nM
12.	ALA5286829	1p	logD	=	1.8		ALA5252392
13.	ALA5286829	1p	INH	=	42.1	%	ALA5252391			%	Homo sapiens
14.	ALA5286829	1p	IC50	=	14	uM	ALA5252388	4.85		nM	Homo sapiens
15.	ALA5286829	1p	IC50	=	4.8	uM	ALA5252387	5.32		nM	Homo sapiens
16.	ALA5286829	1p	IC50	=	0.81	uM	ALA5252385	6.09		nM	Mus musculus
17.	ALA5286829	1p	IC50	=	0.032	uM	ALA5252384	7.50		nM	Homo sapiens