# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5286909 | 19 | INH | = | 57 | % | ALA5258379 | % | ||||
2. | ALA5286909 | 19 | Cp | = | 760 | nM | ALA5258378 | nM | ||||
3. | ALA5286909 | 19 | F | = | 20 | % | ALA5258377 | % | ||||
4. | ALA5286909 | 19 | CL | = | 0.7 | L/hr/kg | ALA5258376 | mL.min-1.kg-1 | ||||
5. | ALA5286909 | 19 | Vdss | = | 0.66 | L/Kg | ALA5258375 | L.kg-1 | ||||
6. | ALA5286909 | 19 | t1/2 | = | 3.2 | hr | ALA5258374 | hr | ||||
7. | ALA5286909 | 19 | AUC | = | 2215 | nM.hr | ALA5258373 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
8. | ALA5286909 | 19 | Cmax | = | 825 | nM | ALA5258372 | nM | ||||
9. | ALA5286909 | 19 | IC50 | = | 184 | nM | ALA5258371 | 6.74 | nM | Homo sapiens | ||
10. | ALA5286909 | 19 | IC50 | > | 10 | uM | ALA5258370 | nM | Homo sapiens | |||
11. | ALA5286909 | 19 | IC50 | > | 10 | uM | ALA5258369 | nM | Homo sapiens | |||
12. | ALA5286909 | 19 | IC50 | > | 10 | uM | ALA5258368 | nM | Homo sapiens | |||
13. | ALA5286909 | 19 | IC50 | > | 10 | uM | ALA5258367 | nM | Homo sapiens | |||
14. | ALA5286909 | 19 | IC50 | > | 10 | uM | ALA5258366 | nM | Homo sapiens | |||
15. | ALA5286909 | 19 | F | = | 100 | % | ALA5258365 | % | ||||
16. | ALA5286909 | 19 | CL | = | 1.4 | L/hr/kg | ALA5258364 | mL.min-1.kg-1 | ||||
17. | ALA5286909 | 19 | Vdss | = | 2.6 | L/Kg | ALA5258363 | L.kg-1 | ||||
18. | ALA5286909 | 19 | t1/2 | = | 6.6 | hr | ALA5258362 | hr | ||||
19. | ALA5286909 | 19 | AUC | = | 5819 | nM.hr | ALA5258361 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
20. | ALA5286909 | 19 | Cmax | = | 5553 | nM | ALA5258360 | nM |