| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5286989 | 12e | BPR | = | 0 | ALA5223858 | ||||||
| 2. | ALA5286989 | 12e | CL | = | 81 | ml/min.kg | ALA5223857 | mL.min-1.kg-1 | ||||
| 3. | ALA5286989 | 12e | Vdss | = | 4.9 | L/Kg | ALA5223856 | L.kg-1 | ||||
| 4. | ALA5286989 | 12e | beta t1/2 | = | 2.3 | hr | ALA5223855 | hr | ||||
| 5. | ALA5286989 | 12e | AUC | = | 16 | ng.hr/ml | ALA5223854 | ng.hr.mL-1 | ||||
| 6. | ALA5286989 | 12e | Cmax | = | 14 | ng/ml | ALA5223853 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 7. | ALA5286989 | 12e | F | = | 2.6 | % | ALA5223852 | % | ||||
| 8. | ALA5286989 | 12e | INH | = | 0 | % | ALA5223851 | % | Homo sapiens | |||
| 9. | ALA5286989 | 12e | IC50 | > | 45 | uM | ALA5223850 | nM | Homo sapiens | |||
| 10. | ALA5286989 | 12e | IC50 | > | 45 | uM | ALA5223849 | nM | Homo sapiens | |||
| 11. | ALA5286989 | 12e | Drug metabolism | = | 62.5 | % | ALA5223846 | % | ||||
| 12. | ALA5286989 | 12e | Drug metabolism | = | 55.1 | % | ALA5223845 | % | ||||
| 13. | ALA5286989 | 12e | Emax | = | 41 | % | ALA5223844 | % | Homo sapiens | |||
| 14. | ALA5286989 | 12e | EC50 | = | 169 | nM | ALA5223843 | 6.77 | nM | Homo sapiens |
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