# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5288610 | 14d | Activity | 0 | ALA5225251 | Active | Mus musculus | |||||
2. | ALA5288610 | 14d | Activity | 0 | ALA5225250 | Dose-Dependent Effect | Mus musculus | |||||
3. | ALA5288610 | 14d | Activity | 0 | ALA5225249 | Active | Mus musculus | |||||
4. | ALA5288610 | 14d | Activity | 0 | ALA5225248 | Dose-Dependent Effect | Mus musculus | |||||
5. | ALA5288610 | 14d | Kp | = | 1.51 | ALA5225247 | ||||||
6. | ALA5288610 | 14d | Kp | = | 5.64 | ALA5225246 | ||||||
7. | ALA5288610 | 14d | Cmax | = | 65.4 | ng/ml | ALA5225245 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA5288610 | 14d | AUC | = | 347 | ng.hr/ml | ALA5225244 | ng.hr.mL-1 | ||||
9. | ALA5288610 | 14d | CL | = | 9.02 | ml/min.kg | ALA5225243 | mL.min-1.kg-1 | ||||
10. | ALA5288610 | 14d | Fu | = | 3.1 | % | ALA5225242 | |||||
11. | ALA5288610 | 14d | Stability | = | 81 | % | ALA5225241 | % | ||||
12. | ALA5288610 | 14d | Stability | = | 91 | % | ALA5225240 | % | ||||
13. | ALA5288610 | 14d | IC50 | > | 20 | uM | ALA5225239 | nM | Homo sapiens | |||
14. | ALA5288610 | 14d | IC50 | > | 20 | uM | ALA5225238 | nM | Homo sapiens | |||
15. | ALA5288610 | 14d | IC50 | > | 20 | uM | ALA5225237 | nM | Homo sapiens | |||
16. | ALA5288610 | 14d | IC50 | > | 20 | uM | ALA5225236 | nM | Homo sapiens | |||
17. | ALA5288610 | 14d | IC50 | > | 20 | uM | ALA5225235 | nM | Homo sapiens | |||
18. | ALA5288610 | 14d | EC150 | = | 0.044 | uM | ALA5225234 | uM | ||||
19. | ALA5288610 | 14d | EC150 | = | 0.002 | uM | ALA5225233 | uM | Homo sapiens |